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Anti-Phospho-YAP1 (S127) Antibody (5V148)

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Catalog No. TMAC-03284

Anti-Phospho-YAP1 (S127) Antibody (5V148) is a Rabbit antibody targeting Phospho-YAP1 (S127). Anti-Phospho-YAP1 (S127) Antibody (5V148) can be used in WB,IHC.

Anti-Phospho-YAP1 (S127) Antibody (5V148)

Anti-Phospho-YAP1 (S127) Antibody (5V148)

😃Good
Catalog No. TMAC-03284
Anti-Phospho-YAP1 (S127) Antibody (5V148) is a Rabbit antibody targeting Phospho-YAP1 (S127). Anti-Phospho-YAP1 (S127) Antibody (5V148) can be used in WB,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4987-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-YAP1 (S127) Antibody (5V148) is a Rabbit antibody targeting Phospho-YAP1 (S127). Anti-Phospho-YAP1 (S127) Antibody (5V148) can be used in WB,IHC.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe Yes-associated protein, otherwise known as YAP, is a 14-3-3-binding molecule that was originally recognized by virtue of its ability to bind to the SH3 domain of Yes. The binding of YAP to 14-3-3 requires the phosphorylation of a homologous serine residue (Ser 112) in the YAP 14-3-3-binding motif. The highly conserved and ubiquitously expressed 14-3-3 proteins regulate differentiation, cell cycle progression and apoptosis by binding intracellular phosphoproteins involved in signal transduction. YAP may link events at the plasma membrane and cytoskeleton to inhibition of transcription in the nucleus in a manner regulated by 14-3-3 proteins. YAP shares homology with the WW domain of TAZ, transcriptional co-activator with PDZ-binding motif, which functions as a transcriptional co-activator by binding to the PPXY motif present in transcription factors. YAP is expressed at high levels in the lung, placenta, prostate, ovary and testis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Human breast carcinoma tissue, human kidney tissue, mouse kidney tissue
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 65 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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