Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes-mainly NK cells, T cells and dendritic cells. Its increased levels in tumors improve the prognosis for cancer patients, although it is also associated with a poorer prognosis in some types of cancers, such as pancreatic ductal adenocarcinoma.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 814.00 | |
500 μg | 5 days | $ 3,250.00 | |
1 mg | 5 days | $ 5,440.00 |
Description | Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes-mainly NK cells, T cells and dendritic cells. Its increased levels in tumors improve the prognosis for cancer patients, although it is also associated with a poorer prognosis in some types of cancers, such as pancreatic ductal adenocarcinoma. |
Species | Mouse |
Expression System | HEK293 |
Tag | C-His-Avi |
Accession Number | O35188 |
Synonyms | Neurotactin, CXC3C, ABCD-3, Fkn, Fractalkine, NTT, Cx3cl1, SCYD1, Cx3c, C3Xkine, CXC3, NTN |
Construction | Recombinant Biotinylated Mouse CX3CL1/Fractalkine Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. It contains Gln25-Thr336.[Accession |O35188] |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Molecular Weight | The protein has a predicted MW of 36 kDa. Due to glycosylation, the protein migrates to 70-83 kDa based on Tris-Bis PAGE result. |
Endotoxin | Less than 1EU per ug by the LAL method. |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability & Storage |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes-mainly NK cells, T cells and dendritic cells. Its increased levels in tumors improve the prognosis for cancer patients, although it is also associated with a poorer prognosis in some types of cancers, such as pancreatic ductal adenocarcinoma. |
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Please read the User Guide of Recombinant Proteins for more specific information.
CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated CXC 3 Neurotactin CXC3C ABCD-3 Fkn Fractalkine NTT Cx3cl1 ABCD3 ABCD 3 SCYD1 Cx3c C3Xkine CXC3 SCYD 1 NTN CXC-3 SCYD-1 recombinant recombinant-proteins proteins protein