CD82 Protein, Human, Recombinant (hFc)

Name: CD82 Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPJ-00157
Rating: 4.5 (1 reviews)

(Synonyms: TSPAN274F9, Tspan-27, TSPAN27, Tetraspanin-27, Suppressor of tumorigenicity 6 protein, ST6tspan-27, ST6, KAI1GR15, KAI1, Inducible membrane protein R2, IA4C33 antigen, IA4, CD82 molecule, CD82 antigenC33, CD82) Copy Product Info

Synonyms: TSPAN274F9, Tspan-27, TSPAN27, Tetraspanin-27, Suppressor of tumorigenicity 6 protein, ST6tspan-27, ST6, KAI1GR15, KAI1, Inducible membrane protein R2, IA4C33 antigen, IA4, CD82 molecule, CD82 antigenC33, CD82

Catalog No. TMPJ-00157 Copy Product Info

CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer.

Pack Size	Price	USA Stock	Global Stock
5 µg	$96	35 days	35 days
10 µg	$157	35 days	35 days
20 µg	$252	35 days	35 days
50 µg	$478	35 days	35 days
100 µg	$773	35 days	35 days
200 µg	$1,250	35 days	35 days
500 µg	$2,390	35 days	35 days
1 mg	$3,600	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer.
Species	Human
Expression System	HEK293 Cells
Tag	N-hFc
Accession Number	P27701
Amino Acid	Gly103-Gln225
Construction	Gly103-Gln225
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	TSPAN274F9, Tspan-27, TSPAN27, Tetraspanin-27, Suppressor of tumorigenicity 6 protein, ST6tspan-27, ST6, KAI1GR15, KAI1, Inducible membrane protein R2, IA4C33 antigen, IA4, CD82 molecule, CD82 antigenC33, CD82
Research Background	CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer.

Chemical Properties

Molecular Weight

40-60 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.