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CD82 Protein, Human, Recombinant (hFc)
(Synonyms: TSPAN274F9, Tspan-27, TSPAN27, Tetraspanin-27, Suppressor of tumorigenicity 6 protein, ST6tspan-27, ST6, KAI1GR15, KAI1, Inducible membrane protein R2, IA4C33 antigen, IA4, CD82 molecule, CD82 antigenC33, CD82) Copy Product InfoSynonyms: TSPAN274F9, Tspan-27, TSPAN27, Tetraspanin-27, Suppressor of tumorigenicity 6 protein, ST6tspan-27, ST6, KAI1GR15, KAI1, Inducible membrane protein R2, IA4C33 antigen, IA4, CD82 molecule, CD82 antigenC33, CD82
Catalog No. TMPJ-00157 Copy Product Info
CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $96 | 35 days | 35 days | |
| 10 μg | $157 | 35 days | 35 days | |
| 20 μg | $252 | 35 days | 35 days | |
| 50 μg | $478 | 35 days | 35 days | |
| 100 μg | $773 | 35 days | 35 days | |
| 200 μg | $1,250 | 35 days | 35 days | |
| 500 μg | $2,390 | 35 days | 35 days | |
| 1 mg | $3,600 | 35 days | 35 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | |
| Description | CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | N-hFc |
| Accession Number | P27701 |
| Amino Acid | Gly103-Gln225 |
| Construction | Gly103-Gln225 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | TSPAN274F9, Tspan-27, TSPAN27, Tetraspanin-27, Suppressor of tumorigenicity 6 protein, ST6tspan-27, ST6, KAI1GR15, KAI1, Inducible membrane protein R2, IA4C33 antigen, IA4, CD82 molecule, CD82 antigenC33, CD82 |
| Research Background |
| Molecular Weight | 40-60 KDa (reducing condition) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Related Tags: CD82 Protein, Human, Recombinant (hFc) chemical structure | CD82 Protein, Human, Recombinant (hFc) molecular weight
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