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CD52 Protein, Cynomolgus, Recombinant (hFc)

(Synonyms: CD52 molecule) Copy Product Info

Synonyms: CD52 molecule

Catalog No. TMPY-05838 Copy Product Info
CD52 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 27.82 kDa and the accession number is A0A8J8Y2J7.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$797-10 days7-10 days
10 µg$1297-10 days7-10 days
20 µg$2087-10 days7-10 days
50 µg$4197-10 days7-10 days
100 µg$8127-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
CD52 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 27.82 kDa and the accession number is A0A8J8Y2J7.
Species
Cynomolgus
Expression System
HEK293 Cells
TagC-hFc
Accession NumberNP_001253116.1
ConstructionA DNA sequence encoding the cynomolgus CD52 (NP_001253116.1) (Met1-Ser35) was expressed with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Ser 25
Protein Purity
> 95 % as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
SynonymsCD52 molecule
Research Background
CD52 / CDW52 is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein. It has a mature peptide comprising only 12 amino acids and is abundantly expressed on human lymphocytes. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52 / CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Chemical Properties
Molecular Weight27.82 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: CD52 Protein, Cynomolgus, Recombinant (hFc) chemical structure | CD52 Protein, Cynomolgus, Recombinant (hFc) molecular weight