Siglec-10 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 59.90 kDa and the accession number is A0A2K5WBX8.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 487.00 | |
500 μg | 5 days | $ 1,950.00 | |
1 mg | 5 days | $ 3,250.00 |
Description | Siglec-10 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 59.90 kDa and the accession number is A0A2K5WBX8. |
Species | Cynomolgus |
Expression System | HEK293 Cells |
Tag | C-His |
Accession Number | A0A2K5WBX8 |
Synonyms | SIGLEC10, PRO940, SLG2, MGC126774 |
Construction | Thr17-Asn552 |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 90% as determined by HPLC |
Molecular Weight | 59.90 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result. |
Endotoxin | < 1 EU/μg by the LAL method. |
Formulation | Supplied as 0.22 μm filtered solution in 25 mM MES, 150 mM NaCl, 0.5M Arginine (pH 5.0). |
Stability & Storage |
It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by a varying number of Ig-like C2-type domains. Siglecs 5-11 constitute the CD33/Siglec-3 related group, and are differentially expressed in the hematopoietic system. |
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Siglec-10 Protein, Cynomolgus, Recombinant (His) SLG-2 SIGLEC 10 SIGLEC10 PRO940 MGC 126774 SLG 2 SIGLEC-10 MGC-126774 SLG2 MGC126774 PRO 940 PRO-940 recombinant recombinant-proteins proteins protein