Home Tools
Log in
Cart

Siglec-10 Protein, Cynomolgus, Recombinant (His)

Catalog No. TMPK-00531
Synonyms: SIGLEC10, PRO940, SLG2, MGC126774

Siglec-10 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 59.90 kDa and the accession number is A0A2K5WBX8.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Siglec-10 Protein, Cynomolgus, Recombinant (His)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 487.00
500 μg 5 days $ 1,950.00
1 mg 5 days $ 3,250.00
Bulk Inquiry
Get quote
Contact us for more batch information
Biological Description
Technical Params
Product Properties
References and Literature
Description Siglec-10 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 59.90 kDa and the accession number is A0A2K5WBX8.
Species Cynomolgus
Expression System HEK293 Cells
Tag C-His
Accession Number A0A2K5WBX8
Synonyms SIGLEC10, PRO940, SLG2, MGC126774
Construction Thr17-Asn552
Protein Purity > 95% as determined by Tris-Bis PAGE; > 90% as determined by HPLC
Molecular Weight 59.90 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
Endotoxin < 1 EU/μg by the LAL method.
Formulation Supplied as 0.22 μm filtered solution in 25 mM MES, 150 mM NaCl, 0.5M Arginine (pH 5.0).
Stability & Storage

It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by a varying number of Ig-like C2-type domains. Siglecs 5-11 constitute the CD33/Siglec-3 related group, and are differentially expressed in the hematopoietic system.

References and Literature

Calculator

Reconstitution Calculator
Recombinant Proteins Dilute Calculator
Specific Activity Calculator
=
÷
X
=
X
(Unit/mg)
= 106 ÷
ng/mL

bottom

Tech Support

Please read the User Guide of Recombinant Proteins for more specific information.

Keywords

Siglec-10 Protein, Cynomolgus, Recombinant (His) SLG-2 SIGLEC 10 SIGLEC10 PRO940 MGC 126774 SLG 2 SIGLEC-10 MGC-126774 SLG2 MGC126774 PRO 940 PRO-940 recombinant recombinant-proteins proteins protein

 

TargetMol