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(R)-5-Hydroxy-1,7-diphenylheptan-3-one

🥰Excellent
Catalog No. TN6339Cas No. 100761-20-4
Alias (5R)-Dihydroyashabushiketol

(R)-5-Hydroxy-1,7-diphenylheptan-3-one ((5R)-Dihydroyashabushiketol) is extracted from the rhizomes of Alpinia officinarum, a Chinese medicinal herb, and inhibits melanogenesis in theophylline-stimulated murine B16 melanoma 4A5 cells.

(R)-5-Hydroxy-1,7-diphenylheptan-3-one
Other Forms of (R)-5-Hydroxy-1,7-diphenylheptan-3-one:
DihydroyashabushiketolT12522824192-01-6
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(R)-5-Hydroxy-1,7-diphenylheptan-3-one

🥰Excellent
Purity: 99.92%
Catalog No. TN6339Alias (5R)-DihydroyashabushiketolCas No. 100761-20-4
(R)-5-Hydroxy-1,7-diphenylheptan-3-one ((5R)-Dihydroyashabushiketol) is extracted from the rhizomes of Alpinia officinarum, a Chinese medicinal herb, and inhibits melanogenesis in theophylline-stimulated murine B16 melanoma 4A5 cells.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$113In StockIn Stock
5 mg$289In StockIn Stock
10 mg$413In StockIn Stock
25 mg$673In StockIn Stock
50 mg$939In StockIn Stock
1 mL x 10 mM (in DMSO)$262In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.92%
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Product Introduction

Bioactivity
Description
(R)-5-Hydroxy-1,7-diphenylheptan-3-one ((5R)-Dihydroyashabushiketol) is extracted from the rhizomes of Alpinia officinarum, a Chinese medicinal herb, and inhibits melanogenesis in theophylline-stimulated murine B16 melanoma 4A5 cells.
Synonyms(5R)-Dihydroyashabushiketol
Chemical Properties
Molecular Weight282.38
FormulaC19H22O2
Cas No.100761-20-4
SmilesO[C@H](CCc1ccccc1)CC(=O)CCc1ccccc1
Relative Density.1.084 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 60 mg/mL (212.48 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (7.08 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.5413 mL17.7066 mL35.4133 mL177.0664 mL
5 mM0.7083 mL3.5413 mL7.0827 mL35.4133 mL
10 mM0.3541 mL1.7707 mL3.5413 mL17.7066 mL
20 mM0.1771 mL0.8853 mL1.7707 mL8.8533 mL
50 mM0.0708 mL0.3541 mL0.7083 mL3.5413 mL
100 mM0.0354 mL0.1771 mL0.3541 mL1.7707 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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% Saline/PBS/ddH2O

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Keywords

oxidative stressNrf2/ARE pathwayKeap1-Nrf2insulin resistanceInhibitorinhibitDihydroyashabushiketoldiarylheptanoidAlpinia officinarum5-Hydroxy-1,7-diphenylheptan-3-one(R)5Hydroxy1,7diphenylheptan3one(R) 5 Hydroxy 1,7 diphenylheptan 3 one
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