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Anti-ADAMTS4 Polyclonal Antibody

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Catalog No. TMAB-00056

Anti-ADAMTS4 Polyclonal Antibody is a Rabbit antibody targeting ADAMTS4. Anti-ADAMTS4 Polyclonal Antibody can be used in WB.

Anti-ADAMTS4 Polyclonal Antibody

Anti-ADAMTS4 Polyclonal Antibody

😃Good
Catalog No. TMAB-00056
Anti-ADAMTS4 Polyclonal Antibody is a Rabbit antibody targeting ADAMTS4. Anti-ADAMTS4 Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$222 7-10 days
100 μL$374 7-10 days
200 μL$528 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Rabbit Polyclonal

Application: WB

Reactivity: Human,Mouse,Rat (predicted:Cow,Rabbit,Sheep)
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Cow,Rabbit,Sheep)
Verified Activity
Sample:
Lane 1: Mouse Cerebrum tissue lysates
Lane 2: Rat Cerebrum tissue lysates
Lane 3: Human A549 cell lysates
Primary: Anti-ADAMTS4 (TMAB-00056) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 90 kDa
Observed band size: 100 kDa
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted. extracellular space. extracellular matrix.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundThis gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The expression of this gene is upregulated in arthritic disease and this may contribute to disease progression through the degradation of aggrecan. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human ADAMTS4
Antigen Species
Human
Gene ID
9507
Uniprot ID
Biology Area
MMP,ADAM Protein Family,ADAM TS,ADAM protein family
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Sci Citations

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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