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Anti-Carboxypeptidase B1 Antibody (9Y858) is a Rabbit antibody targeting Carboxypeptidase B1. Anti-Carboxypeptidase B1 Antibody (9Y858) can be used in ELISA,IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-Carboxypeptidase B1 Antibody (9Y858) is a Rabbit antibody targeting Carboxypeptidase B1. Anti-Carboxypeptidase B1 Antibody (9Y858) can be used in ELISA,IHC-P. |
Alias | carboxypeptidase B1 (tissue), AI504870, 2210008M23Rik, 1810063F02Rik, 0910001A18Rik |
Ig Type | Monoclonal Rabbit IgG |
Clone | 9Y858 |
Reactivity | Human |
Verified Activity | Immunochemical staining of human CPB1 in human pancreas with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. |
Application | ELISA,IHC-P |
Recommended Dose | ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Carboxypeptidase B1 / CPB1 (rh Carboxypeptidase B1 / CPB1; TMPY-00727; NP_001862.2; Met 1-Tyr 417). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Carboxypeptidase B1, also well known as pancreatic procarboxypeptidase B (PCPB), is a highly pancreas -specific protein (PASP), and has been identified previously as a serum marker for acute pancreatitis and pancreatic graft rejection. As the prototype for those human exopeptidases that cleave off basic C-terminal residues, CPB1 specifically cleaves the C-terminal Arg and Lys residues with a preference for Arg. The B1 and B2 forms of procarboxypeptidase B differ from each other mainly in isoelectric point.The deduced amino acid sequence of PCPB predicts a 416-amino acid preproenzyme consisting of a 15-aa signal peptide, a 95-aa activation peptide and a 37-aa mature chain. The secreted PCPB zymogen is converted to enzymatically active CPB1 by limited proteolysis by trypsin. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human Carboxypeptidase B1 / CPB1 protein (TMPY-00727) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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