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Pateclizumab
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Catalog No. T77366Cas No. 1202526-59-7
Alias RG7416, RG 7416, PRO283698, PRO 283698, MLTA3698A, MLTA 3698A
Pateclizumab (MLTA3698A) is a humanized monoclonal antibody targeting lymphotoxin α (LTα), which can be used to study rheumatoid arthritis.
Pateclizumab
Pateclizumab
😃Good
Catalog No. T77366Alias RG7416, RG 7416, PRO283698, PRO 283698, MLTA3698A, MLTA 3698ACas No. 1202526-59-7
Pateclizumab (MLTA3698A) is a humanized monoclonal antibody targeting lymphotoxin α (LTα), which can be used to study rheumatoid arthritis.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $415 | - | In Stock | |
| 5 mg | $1,245 | - | In Stock | |
| 10 mg | $1,992 | - | In Stock | |
| 25 mg | $3,386 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:96.96% (SEC-HPLC)
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| Description | Pateclizumab (MLTA3698A) is a humanized monoclonal antibody targeting lymphotoxin α (LTα), which can be used to study rheumatoid arthritis. |
| In vitro | Pateclizumab is a human immunoglobulin G1 (IgG1) monoclonal antibody. By blocking the binding of Lα3 to TNFRII and Lα1β2 to Lβr, the IC50 was 0.29 nM and 0.31 nM, respectively. [1] |
| In vivo | In cynomolgus monkeys treated with pateclizumab (5, 15, 50 mg/kg), the ratio of fetal to maternal serum concentration was 0.73% on GD 50 and 61% on GD 139. Taking Pateclizumab between the 20th and 132nd days of gestation does not induce maternal or fetal developmental toxicity. [1] |
| Synonyms | RG7416, RG 7416, PRO283698, PRO 283698, MLTA3698A, MLTA 3698A |
| Reactivity | Human |
| Verified Activity | Immobilized human TNFSF1/TNFb Protein (His) at 2 μg/mL can bind Pateclizumab. The EC50 is 0.01351 μg/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | TNFSF1/TNFb/ LT alpha |
| Molecular Weight | 144.9 kDa |
| Cas No. | 1202526-59-7 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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