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Pateclizumab (Synonyms: RG7416, RG 7416, PRO283698, PRO 283698, MLTA3698A, MLTA 3698A)
Catalog No. T77366 Copy Product Info
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Pateclizumab (MLTA3698A) is a humanized monoclonal antibody targeting lymphotoxin α (LTα), which can be used to study rheumatoid arthritis.
Pateclizumab
Copy Product Info🥰Excellent
Catalog No. T77366
Synonyms RG7416, RG 7416, PRO283698, PRO 283698, MLTA3698A, MLTA 3698A
Pateclizumab (MLTA3698A) is a humanized monoclonal antibody targeting lymphotoxin α (LTα), which can be used to study rheumatoid arthritis.
Pateclizumab
Cas No. 1202526-59-7
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $415 | - | In Stock | |
| 5 mg | $1,245 | - | In Stock | |
| 10 mg | $1,992 | - | In Stock | |
| 25 mg | $3,386 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:96.96% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
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Related Conjugates and Formulations
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Chemical Properties
Antibody Information
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| Description | Pateclizumab (MLTA3698A) is a humanized monoclonal antibody targeting lymphotoxin α (LTα), which can be used to study rheumatoid arthritis. |
| In vitro | Pateclizumab is a human immunoglobulin G1 (IgG1) monoclonal antibody. By blocking the binding of Lα3 to TNFRII and Lα1β2 to Lβr, the IC50 was 0.29 nM and 0.31 nM, respectively. [1] |
| In vivo | In cynomolgus monkeys treated with pateclizumab (5, 15, 50 mg/kg), the ratio of fetal to maternal serum concentration was 0.73% on GD 50 and 61% on GD 139. Taking Pateclizumab between the 20th and 132nd days of gestation does not induce maternal or fetal developmental toxicity. [1] |
| Synonyms | RG7416, RG 7416, PRO283698, PRO 283698, MLTA3698A, MLTA 3698A |
| Reactivity | Human |
| Verified Activity | Immobilized human TNFSF1/TNFb Protein (His) at 2 μg/mL can bind Pateclizumab. The EC50 is 0.01351 μg/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | TNFSF1/TNFb/ LT alpha |
| Molecular Weight | 144.9 kDa |
| Cas No. | 1202526-59-7 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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