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Pateclizumab
(Synonyms: RG7416, RG 7416, PRO283698, PRO 283698, MLTA3698A, MLTA 3698A) Copy Product Info
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Synonyms: RG7416, RG 7416, PRO283698, PRO 283698, MLTA3698A, MLTA 3698A
Catalog No. T77366 Copy Product Info
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Pateclizumab (MLTA3698A) is a humanized monoclonal antibody targeting lymphotoxin α (LTα), which can be used to study rheumatoid arthritis.
Cas No. 1202526-59-7
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $415 | - | In Stock | |
| 5 mg | $1,245 | - | In Stock | |
| 10 mg | $1,992 | - | In Stock | |
| 25 mg | $3,386 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:96.96% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Pateclizumab (MLTA3698A) is a humanized monoclonal antibody targeting lymphotoxin α (LTα), which can be used to study rheumatoid arthritis. |
| In vitro | Pateclizumab is a human immunoglobulin G1 (IgG1) monoclonal antibody. By blocking the binding of Lα3 to TNFRII and Lα1β2 to Lβr, the IC50 was 0.29 nM and 0.31 nM, respectively. [1] |
| In vivo | In cynomolgus monkeys treated with pateclizumab (5, 15, 50 mg/kg), the ratio of fetal to maternal serum concentration was 0.73% on GD 50 and 61% on GD 139. Taking Pateclizumab between the 20th and 132nd days of gestation does not induce maternal or fetal developmental toxicity. [1] |
| Synonyms | RG7416, RG 7416, PRO283698, PRO 283698, MLTA3698A, MLTA 3698A |
| Reactivity | Human |
| Verified Activity | Immobilized human TNFSF1/TNFb Protein (His) at 2 μg/mL can bind Pateclizumab. The EC50 is 0.01351 μg/mL. |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | TNFSF1/TNFb/ LT alpha |
| Molecular Weight | 144.9 kDa |
| Cas No. | 1202526-59-7 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Pateclizumab chemical structure | Pateclizumab in vivo | Pateclizumab in vitro | Pateclizumab molecular weight
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