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Carbon-13 Labeled Compounds

Carbon-13 labeled compounds are chemical compounds in which one or more carbon atoms are replaced by the stable isotope carbon-13 (¹³C). Carbon-13 has one more neutron than the most common carbon isotope, carbon-12 (¹²C), making it heavier but stable and non-radioactive.

FilterHomeIsotope productsCarbon-13 Labeled Compounds
L-Lysine-13C6-15N2 Hydrochloride
TMIJ-03801200447-00-2
L-Lysine-13C6-15N2 Hydrochloride is L-Lysine hydrochloride labeled with 13C and 15N isotopes. L-Lysine hydrochloride is an essential amino acid for humans and a common food additive. It stimulates the secretion of pepsin and gastric acid, enhances gastric juice secretion, and promotes growth and development in children.
  • $44
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Phenol-13C6
T3803589059-34-7
Phenol-13C6 is a 13C-labeled Phenol, which is an important chemical raw material used in the manufacture of fungicides and herbicides.
  • $61
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D-Fructose-13C6
T35618201595-65-5
D-Fructose-13C6 can be used as an internal standard for the quantification of D-fructose by GC- or LC-MS.
  • $49
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L-Leucine-1-13C
T3281174292-94-7
L-Leucine-1-13C (L-Leucine-13C) is a 13C-labeled L-Leucine that significantly enhances the affinity of GLP-4.
  • $30
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Vancomycin-C13,D3
TMID-0283
Vancomycin-C13,D3 is a compound labeled with 13C and 2H. Vancomycin is a glycopeptide antibiotic that exerts antibacterial activity by altering cell membrane permeability and selectively inhibiting RNA synthesis.
  • $5,800
7-10 days
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Apalutamide-13C-d3
TMIH-0092
Apalutamide-13C-d3 (RN-509-13C,d3) is a 13C and 2H-labeled version of Apalutamide. Apalutamide is an efficient androgen receptor (AR) antagonist used in the study of prostate diseases.
  • $728
7-10 days
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Riluzole-13C,15N2
T376081215552-03-6
Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole. Riluzole is a glutamate antagonist with anticonvulsant activity, inhibiting GABA reuptake and used in ALS research.
  • $891
35 days
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Binimetinib-13C-d3
TMIH-0117
Binimetinib-13C-d3 (MEK162-13C-d3) is an isotopically labelled compound of Binimetinib for use as a tracer.Binimetinib (ARRY-162) is a selective MEK1 2 inhibitor for the treatment of melanoma.
  • $857
7-10 days
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Apixaban 13C,d3
T103491261393-15-0
Apixaban 13C,d3 is a deuterium labeling of Apixaban for isotopic tracing. Apixaban 13C,d3 is a selective inhibitor of coagulation factor Xa and is used in thromboembolism studies
  • $123
7-10 days
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Cyanuric acid-13C3
T39424201996-37-4
Cyanuric acid-13C3 is 13C labeled Cyanuric acid.
  • $198
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Erlotinib-13C6
T359151211107-68-4
Erlotinib-13C6 (CP-358774-13C6) is a 13C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1]. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer[1].Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process[2]. [1]. Moyer JD, et al. Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res. 1997, 57(21), 4838-4848.[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
  • $1,988
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Aflatoxin G2-13C17
T355211217462-49-1
Aflatoxin G2-13C17is intended for use as an internal standard for the quantification of aflatoxin G2by GC- or LC-MS. Aflatoxin G2is a mycotoxin that has been found inAspergillus.1It is lethal to ducklings (LD50= 2.83 mg/kg) but is non-toxic to rats when administered at a dose of 200 mg/kg.2 1.Bennett, J.W., and Klich, M.MycotoxinsClin. Microbiol. Rev.16(3)497-516(2003) 2.Wogan, G.N., Edwards, G.S., and Newberne, P.M.Structure-activity relationships in toxicity and carcinogenicity of aflatoxins and analogsCancer Res.31(12)1936-1942(1971)
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4-Trifluoromethylsalicylic acid-13C6
T386381246817-12-8
4-Trifluoromethylsalicylic acid-13C6 is 13C-labeled 4-Trifluoromethylsalicylic acid, mainly used as a quantitative tracer in drug development. 4-Trifluoromethylsalicylic acid is also a platelet aggregation inhibitor.
  • $669
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Oleic Acid-13C
T3569582005-44-5
Oleic acid-13C is intended for use as an internal standard for the quantification of oleic acid by GC- or LC-MS. Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been found in human plasma, cell membranes, and adipose tissue.1,2 It contributes approximately 17% of the total fatty acids esterified to phosphatidylcholine, the major phospholipid class in porcine platelets.1 Oleic acid inhibits collagen-stimulated platelet aggregation by approximately 90% when used at a concentration of 10 μg/ml. It also inhibits fMLF-induced neutrophil aggregation and degranulation by 55 and 68%, respectively, when used at a concentration of 5 μM, similar to arachidonic acid .3 Oleic acid (60 μM) induces release of intracellular calcium in human platelets.4
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    2-Nitrobenzaldehyde semicarbazone 13C,15N2
    T40874760179-80-4
    2-Nitrobenzaldehyde semicarbazone (13C, 15N2) is utilized in the LC-MS/MS method for semicarbazide analysis.
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    1,2-Dioleoyl-rac-glycerol-13C3
    T370441173097-49-8
    1,2-Dioleoyl-rac-glycerol-13C3 is intended for use as an internal standard for the quantification of 1,2-dioleoyl-rac-glycerol by GC- or LC-MS. 1,2-dioleoyl-rac-glycerol is a diacylglycerol that contains oleic acid at the sn-1 and sn-2 positions. It effectively binds the C1 domain to activate conventional protein kinase C forms and serves as a substrate for diacylglycerol kinases and multisubstrate lipid kinase.1,2,3 |1. Yamaguchi, Y., Shirai, Y., Matsubara, T., et al. Phosphorylation and up-regulation of diacylglycerol kinase γ via its interaction with protein kinase Cγ. J. Biol. Chem. 281(42), 31627-31637 (2006).|2. Zhou, Q.Z., Raynor, R.L., Wood, M.G., Jr., et al. Structure-activity relationship of synthetic branched-chain distearoylglycerol (distearin) as protein kinase C activators. Biochemistry 27(19), 7361-7365 (1988).|3. Epand, R.M., Shulga, Y.V., Timmons, H.C., et al. Substrate chirality and specificity of diacylglycerol kinases and the multisubstrate lipid kinase. Biochemistry 46(49), 14225-14231 (2007).
    • $73
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    Palmitic acid-1-13C
    T3578957677-53-9
    Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.1 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.2 Palmitic acid is involved in the acylation of proteins to anchor membrane-bound proteins to the lipid bilayer.2,3,4,5,6 |1. Santos, M.J., López-Jurado, M., Llopis, J., et al. Influence of dietary supplementation with fish oil on plasma fatty acid composition in coronary heart disease patients. Ann. Nutr. Metab. 39(1), 52-62 (1995).|2. Lee, J.Y., Sohn, K.H., Rhee, S.H., et al. Saturated fatty acids, but not unsaturated fatty acids, induced the expression of cyclooxygenase-2 mediated through toll-like receptor 4. J. Biol. Chem. 276(20), 16683-16689 (2001).|3. Dietzen, D.J., Hastings, W.R., and Lublin, D.M. Caveolin is palmitoylated on multiple cysteine residues. Palmitoylation is not necessary for localization of caveolin to caveolae. J. Biol. Chem. 270(12), 6838-6842 (1995).|4. Robinson, L.J., and Michel, T. Mutagenesis of palmitoylation sites in endothelial nitric oxide synthase identifies a novel motif for dual acylation and subcellular targeting. Proc. Nat. Acad. Sci. USA 92(25), 11776-11780 (1995).|5. Topinka, J.R., and Bredt, D.S. N-terminal palmitoylation of PSD-95 regulates association with cell membranes and interaction with K+ channel Kv1.4. Neuron 20(1), 125-134 (1998).|6. Miggin, S.M., Lawler, O.A., and Kinsella, B.T. Palmitoylation of the human prostacyclin receptor. Functional implications of palmitoylation and isoprenylation. J. Biol. Chem. 278(9), 6947-6958 (2003).
    • $36
    7-10 days
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    2,4-Dichlorophenol-13C6
    TMIJ-03561202864-83-2
    2,4-Dichlorophenol-13C6 the 13C and deuterated compound of 2,4-Dichlorophenol. 2,4-Dichlorophenol has a CAS number of 120-83-2. 2,4-Dichlorophenol is the precursor to the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D).
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    20 days
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    trans-Hydroxy Loxoprofen-13C-d3
    TMIJ-0212
    trans-Hydroxy Loxoprofen-13C-d3 (Mixture of Diastereomers) the 13C and deuterated compound of trans-Hydroxy Loxoprofen. trans-Hydroxy Loxoprofen has a CAS number of 371753-19-4.
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    Ethyl Acetate-13C2
    TMIJ-052584508-45-2
    Ethyl Acetate-13C2 is the 13C labeled compound of Ethyl Acetate. Ethyl Acetate has a CAS number of 141-78-6.
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    Nicergoline-13C-d3
    TMIJ-0251
    Nicergoline-13C-d3 the 13C and deuterated compound of Nicergoline. Nicergoline has a CAS number of 27848-84-6. Nicergoline is an ergot derivative used to treat senile dementia and other disorders with vascular origins.
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    Lercanidipine-13C-d3 HCl
    TMIJ-0187
    Lercanidipine-13C-d3 HCl the 13C and deuterated compound of Lercanidipine HCl. Lercanidipine HCl has a CAS number of 132866-11-6. Lercanidipine is a calcium channel blocker of the dihydropyridine class.
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    20 days
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    Ondansetron-13C-d3
    TMIJ-0191
    Ondansetron-13C-d3 the 13C and deuterated compound of Ondansetron. Ondansetron has a CAS number of 99614-02-5. Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.
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    Benzophenone-13C (carbonyl-13C)
    TMIJ-052232488-48-5
    Benzophenone-13C (carbonyl-13C) is the 13C labeled compound of Benzophenone. Benzophenone has a CAS number of 119-61-9.
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    20 days
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