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PfLDH Protein, P. falciparum, Recombinant (His)

TargetMol | SPR
Catalog No. TMPY-04180 Copy Product Info
Plasmodium falciparum lactate dehydrogenase (PfLDH) is a key enzyme for energy generation of malarial parasites and is considered to be a potential antimalarial target. The ability of PfLDH- or PfIDEh-based immuno-PCR assays to detect <1 parasite/microL suggests that improvements of bound antibody sensor technology may greatly increase the sensitivity of malaria rapid diagnostic tests. The PfLDH test could be used to detect failures and, therefore, to assess anti-malarial efficacy.

PfLDH Protein, P. falciparum, Recombinant (His)

Catalog No. TMPY-04180
Copy Product Info
TargetMol | SPR

Plasmodium falciparum lactate dehydrogenase (PfLDH) is a key enzyme for energy generation of malarial parasites and is considered to be a potential antimalarial target. The ability of PfLDH- or PfIDEh-based immuno-PCR assays to detect <1 parasite/microL suggests that improvements of bound antibody sensor technology may greatly increase the sensitivity of malaria rapid diagnostic tests. The PfLDH test could be used to detect failures and, therefore, to assess anti-malarial efficacy.

PfLDH Protein, P. falciparum, Recombinant (His)
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$557-10 days7-10 days
10 μg$867-10 days7-10 days
20 μg$1397-10 days7-10 days
50 μg$2697-10 days7-10 days
100 μg$451In StockIn Stock
200 μg$7987-10 days7-10 days
500 μg$1,6907-10 days7-10 days
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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)
For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Information

Biological Activity
Measured by its ability to reduce pyruvate to lactate. The specific activity is >50,000 pmoles/min/μg.
Description
Plasmodium falciparum lactate dehydrogenase (PfLDH) is a key enzyme for energy generation of malarial parasites and is considered to be a potential antimalarial target. The ability of PfLDH- or PfIDEh-based immuno-PCR assays to detect <1 parasite/microL suggests that improvements of bound antibody sensor technology may greatly increase the sensitivity of malaria rapid diagnostic tests. The PfLDH test could be used to detect failures and, therefore, to assess anti-malarial efficacy.
Species
P. falciparum
Expression System
E. coli
TagC-His
Accession NumberQ76NM3
Synonyms
PfLDH,L-lactate dehydrogenase
Construction
A DNA sequence encoding the PfLDH (XP_001349989.1) (Met1-Ala316) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Met
Protein Purity
> 95 % as determined by SDS-PAGE
PfLDH Protein, P. falciparum, Recombinant (His)
Molecular Weight34.9 kDa (predicted)
EndotoxinPlease contact us for more information.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution
Reconstituted with sterile deionized water to 0.15 mg/mL. Reconstitution conditions may vary depending on the lot.
Stability & Storage
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background
Plasmodium falciparum lactate dehydrogenase (PfLDH) is a key enzyme for energy generation of malarial parasites and is considered to be a potential antimalarial target. The ability of PfLDH- or PfIDEh-based immuno-PCR assays to detect <1 parasite/microL suggests that improvements of bound antibody sensor technology may greatly increase the sensitivity of malaria rapid diagnostic tests. The PfLDH test could be used to detect failures and, therefore, to assess anti-malarial efficacy.

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