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Oxyimperatorin
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Catalog No. TN2024Cas No. 35740-18-2
Oxyimperatorin is a natural product from Angelica dahurica.
Oxyimperatorin
Copy Product Info🥰Excellent
Purity: 99.18%
Catalog No. TN2024Cas No. 35740-18-2
Oxyimperatorin is a natural product from Angelica dahurica.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $53 | In Stock | In Stock | |
| 5 mg | $137 | In Stock | In Stock | |
| 10 mg | $208 | In Stock | In Stock | |
| 25 mg | $346 | In Stock | In Stock | |
| 50 mg | $493 | In Stock | In Stock | |
| 100 mg | $653 | In Stock | - | |
| 1 mL x 10 mM (in DMSO) | $171 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
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Purity:99.18%
Color:White
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Product Introduction
Oxyimperatorin AI Summary
Oxyimperatorin exhibits a broad spectrum of bioactivities. It inhibits nitric oxide generation in lipopolysaccharide and interferon-gamma induced mouse macrophage RAW 264.7 cells with a 36.9% inhibition rate. This compound shows inhibitory activity against RecQ-Like Dna Helicase 1 (RECQ1) with a potency of 5011.9 nM and modulates lipid storage in Drosophila S3 cells with a potency of 290.9 nM. It also inhibits Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia (17740.7 nM) and AmpC Beta-Lactamase (707.9 nM). Furthermore, it inhibits Cell Surface uPA generation (7079.5 nM) and the binding or entry of Marburg Virus into cells (3264.3 nM). In cancer research, Oxyimperatorin shows variable growth inhibition across different human tumor cell lines, with GI50 values between below 40,000 nM and 100,000 nM. Moreover, it possesses antiviral activity against HIV in human H9 cells, with an EC50 value of 2.37 μg/mL, indicating potential efficacy in inhibiting HIV replication..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Oxyimperatorin is a natural product from Angelica dahurica. |
| Molecular Weight | 286.28 |
| Formula | C16H14O5 |
| Cas No. | 35740-18-2 |
| Smiles | CC1(C)OC1COc1c2occc2cc2ccc(=O)oc12 |
| Relative Density. | 1.32g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||
| Solubility Information | DMSO: 3.6 mg/mL (12.58 mM), Sonication is recommended.  | ||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (3.49 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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