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Anti-GIP Polyclonal Antibody
😃Good
Catalog No. TMAB-00770
Alias Incretin, GIP
Anti-GIP Polyclonal Antibody is a Rabbit antibody targeting GIP. Anti-GIP Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P.
Anti-GIP Polyclonal Antibody
Anti-GIP Polyclonal Antibody
😃Good
Catalog No. TMAB-00770Alias Incretin, GIP
Anti-GIP Polyclonal Antibody is a Rabbit antibody targeting GIP. Anti-GIP Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-GIP Polyclonal Antibody is a Rabbit antibody targeting GIP. Anti-GIP Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P. |
| Synonyms | Incretin, GIP |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Pig,Cow) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (mouse intestine tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (GIP) Polyclonal Antibody, Unconjugated (TMAB-00770) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.  |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | GIP (Gastric Inhibitory polypeptide ) belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion. Mature GIP is a highly conserved 42 amino acid polypeptide belonging to the glucagon family. GIP is highly expressed as a pre-pro-protein in the duodenum and the jejunum. The mature secreted polypeptide acts as a potent stimulator of insulin secretion and a poor inhibitor of gastric acid secretion. |
| Immunogen | KLH conjugated synthetic peptide: human GIP |
| Antigen Species | Human |
| Gene Name | GIP |
| Gene ID | |
| Protein Name | Gastric inhibitory polypeptide |
| Uniprot ID | |
| Biology Area | Hormones,Insulin / Insulin-like,GPCR |
| Function | Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion. |
| Molecular Weight | Theoretical: 5/17 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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