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Synonyms: type III preprocollagen alpha 1 chain, Type III collagen, Fetal collagen, Ehlers Danlos syndrome type IV, autosomal dominant, EDS4A, Collagen type III alpha 1(Ehlers Danlos syndrome type IV autosomal dominant), Collagen type III alpha 1, Collagen type III alpha, Collagen III alpha 1 polypeptide, Collagen III alpha 1 chain precursor, Collagen alpha 1(III) chain, COL3A1, COL 3A1, CO3A1
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
| Description | Anti-Collagen III/COL3A1 Polyclonal Antibody 2 is a Rabbit antibody targeting Collagen III/COL3A1. Anti-Collagen III/COL3A1 Polyclonal Antibody 2 can be used in FCM,ICC/IF,WB. |
| Synonyms | type III preprocollagen alpha 1 chain, Type III collagen, Fetal collagen, Ehlers Danlos syndrome type IV, autosomal dominant, EDS4A, Collagen type III alpha 1(Ehlers Danlos syndrome type IV autosomal dominant), Collagen type III alpha 1, Collagen type III alpha, Collagen III alpha 1 polypeptide, Collagen III alpha 1 chain precursor, Collagen alpha 1(III) chain, COL3A1, COL 3A1, CO3A1 |
| Ig Type | IgG |
| Reactivity | Human (predicted:Chicken,Dog,Cow) |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 1ug/Test; ICC/IF: 1:50-200 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted, extracellular space, extracellular matrix. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function. This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. |
| Immunogen | KLH conjugated synthetic peptide: human Collagen alpha 1(III) chain |
| Antigen Species | Human |
| Gene Name | COL3A1 |
| Gene ID | |
| Protein Name | Collagen alpha-1(III) chain |
| Uniprot ID | |
| Biology Area | Collagen,Chondrogenesis,Osteogenesis |
| Function | Collagen type III occurs in most soft connective tissues along with type I collagen. |
| Molecular Weight | Theoretical: 117 kDa. Actual: 150-200 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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