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Decyl-TPP bromide

🥰Excellent
Catalog No. T19662Cas No. 32339-43-8
Alias Triphenyldecylphosphonium·bromide, Decyltriphenylphosphonium bromide, Decyl-TPP, DecylTPP, Decyl TPP. (1-Decyl)triphenylphosphonium bromide, (1-Decyl)triphenylphosphonium bromide

Decyl-TPP bromide ((1-Decyl)triphenylphosphonium bromide) may be used as an intermediate for chemical synthesis and an inactive control or as a reference to mitoquinone (MitoQ).

Decyl-TPP bromide

Decyl-TPP bromide

🥰Excellent
Catalog No. T19662Alias Triphenyldecylphosphonium·bromide, Decyltriphenylphosphonium bromide, Decyl-TPP, DecylTPP, Decyl TPP. (1-Decyl)triphenylphosphonium bromide, (1-Decyl)triphenylphosphonium bromideCas No. 32339-43-8
Decyl-TPP bromide ((1-Decyl)triphenylphosphonium bromide) may be used as an intermediate for chemical synthesis and an inactive control or as a reference to mitoquinone (MitoQ).
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Product Introduction

Bioactivity
Description
Decyl-TPP bromide ((1-Decyl)triphenylphosphonium bromide) may be used as an intermediate for chemical synthesis and an inactive control or as a reference to mitoquinone (MitoQ).
Cell Research
1. As a mitochondrial membrane potential probe
1. Solution preparation: Dissolve Decyl-TPP bromide in a suitable solvent (e.g., ethanol or DMSO) to prepare a stock solution with a concentration typically between 1-10 mM.
2. Treatment: Add the solution to cell culture or tissue, and the use concentration is typically between 1-5 μM.
3. Fluorescence measurement: Decyl-TPP bromide accumulates in mitochondria, and its emission light (typically at 470 nm, with an excitation wavelength of 360 nm) can be measured by a fluorescence spectrophotometer or fluorescence microscope.
4. Data interpretation: Decyl-TPP can be used as a reference or control compound to assess changes in mitochondrial membrane potential, such as comparative studies with other mitochondrial-targeted compounds such as Mitoquinone (MitoQ).
2. Mitochondrial-targeted studies
Compound comparison: In experiments involving Mitoquinone or other mitochondrial-targeted antioxidants, Decyl-TPP can be used as a control compound to study the effects of these compounds on mitochondrial health and function. b. Assessment of mitochondrial function: By comparing Decyl-TPP fluorescence intensity and mitochondrial accumulation, researchers can evaluate the effects of these compounds on key mitochondrial processes such as mitochondrial membrane potential and reactive oxygen species (ROS) generation.
III. As an inactive control in antioxidant studies
1. Control experiments: Decyl-TPP bromide is used together with active mitochondrial-targeted antioxidants or compounds in cell culture or animal models.
2. Effect comparison: Evaluate the effects of these compounds on oxidative stress markers, mitochondrial membrane potential, and cell health, and analyze the effects of experimental compounds by comparison with Decyl-TPP.
IV. Use in mitochondrial dysfunction models
1. Treatment: Decyl-TPP bromide is added to cell culture or animal models that have induced mitochondrial dysfunction (e.g., oxidative stress, metabolic inhibitor treatment).
2. Observation: Track changes in mitochondrial membrane potential and mitochondrial damage by measuring the fluorescence of Decyl-TPP bromide.
AliasTriphenyldecylphosphonium·bromide, Decyltriphenylphosphonium bromide, Decyl-TPP, DecylTPP, Decyl TPP. (1-Decyl)triphenylphosphonium bromide, (1-Decyl)triphenylphosphonium bromide
Chemical Properties
Molecular Weight483.46
FormulaC28H36BrP
Cas No.32339-43-8
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: Soluble

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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