Siglec-6 Protein, Human, Recombinant (His)

Name: Siglec-6 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-06349
Rating: 4.5 (1 reviews)

(Synonyms: SIGLEC6, sialic acid binding Ig like lectin 6, OBBP1, CDW327, CD33L2, CD33L1, CD33L, CD327) Copy Product Info

Synonyms: SIGLEC6, sialic acid binding Ig like lectin 6, OBBP1, CDW327, CD33L2, CD33L1, CD33L, CD327

Catalog No. TMPY-06349 Copy Product Info

Siglec-6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.24 kDa and the accession number is NP_942142.3.

Pack Size	Price	USA Stock	Global Stock
5 µg	$68	7-10 days	7-10 days
10 µg	$108	7-10 days	7-10 days
20 µg	$178	7-10 days	7-10 days
50 µg	$359	7-10 days	7-10 days
100 µg	$696	7-10 days	7-10 days
200 µg	$1,060	7-10 days	7-10 days
500 µg	$2,230	7-10 days	7-10 days
1 mg	$4,530	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:≥ 90 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Siglec-6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.24 kDa and the accession number is NP_942142.3.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	NP_942142.3
Construction	A DNA sequence encoding the human SIGLEC6 (NP_942142.3) (Gln27-Val331) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Ser
Protein Purity	> 90 % as determined by SDS-PAGE.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	SIGLEC6, sialic acid binding Ig like lectin 6, OBBP1, CDW327, CD33L2, CD33L1, CD33L, CD327
Research Background	SIGLEC6, also known as CD327, belongs to the immunoglobulin superfamily, SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC6 is a sialic acid recognizing protein expressed at high levels in placenta (cyto- and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine. SIGLEC6 localizes in various compartments such as membrane fraction, extracellular region and so on. SIGLEC6 may show increasing expression human labor and following childbirth, it has been speculated that this expression helps to slow the tempo of human labor. Interestingly, expression of SIGLEC6 is further upregulated in pre-eclampsia, which appears to be a uniquely human disease.

Chemical Properties

Molecular Weight

35.24 kDa (predicted); 57.07 kDa (reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.