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Anti-IL-7R alpha/CD127 Polyclonal Antibody
😃Good
Catalog No. TMAB-00965
Anti-IL-7R alpha/CD127 Polyclonal Antibody is a Rabbit antibody targeting IL-7R alpha/CD127. Anti-IL-7R alpha/CD127 Polyclonal Antibody can be used in WB.
Anti-IL-7R alpha/CD127 Polyclonal Antibody
Anti-IL-7R alpha/CD127 Polyclonal Antibody
😃Good
Catalog No. TMAB-00965
Anti-IL-7R alpha/CD127 Polyclonal Antibody is a Rabbit antibody targeting IL-7R alpha/CD127. Anti-IL-7R alpha/CD127 Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $220 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-IL-7R alpha/CD127 Polyclonal Antibody is a Rabbit antibody targeting IL-7R alpha/CD127. Anti-IL-7R alpha/CD127 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Sheep) |
| Verified Activity | Sample: Lane 1: Mouse Spleen tissue lysates Lane 2: Mouse Thymus tissue lysates Lane 3: Mouse LympHnode tissue lysates Lane 4: Mouse Lung tissue lysates Lane 5: Rat Spleen tissue lysates Lane 6: Rat Thymus tissue lysates Lane 7: Human K562 cell lysates Lane 8: Human U-2 OS cell lysates Lane 9: Human U-87 MG cell lysates Primary: Anti-IL-7Ra (TMAB-00965) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 50 kDa Observed band size: 70 kDa |
| Application | WB |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted and Cell membrane. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). |
| Immunogen | KLH conjugated synthetic peptide: human IL-7Ra |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Interleukins,B Lymphocytic Lineage,T Lymphocytic Lineage,Monocytic Lineage |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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