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Immune Checkpoint Proteins Immune Checkpoint ProteinsButyrophilins
Butyrophilins are membrane proteins belonging to the immunoglobulin superfamily (Ig). Butyrophilin (Btn) genes constitute a subgroup of at least 10 genes in the Ig superfamily identified in human, mouse, cow, goat and other species. The eponymous Btn gene (BTN1A1 in humans; Btn1a1 in mouse) is highly expressed in the secretory epithelium of the mammary gland during lactation. Other homologues are predominantly expressed in skeletal muscle and the intestine and erythroid cells. In contrast, BTN2A1 and 2 and BTN3A1, 2, and 3 are widely expressed in many tissues, suggesting that the structural domains of Btn proteins may have both universal and tissue-specific functions.
BTN3A1 Protein, Human, Recombinant (His)
TMPY-04844
BTN3A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is O00481-2.
- $451
Size
QTY
SPR-compatible buffer
BTN3A2 Protein, Human, Recombinant (His)
TMPY-04779
Expression system: HEK293 Cells
Length: 1-248, Extracellular Domain
Activity: Not Tested
Length: 1-248, Extracellular Domain
Activity: Not Tested
- $386
Size
QTY
SPR-compatible buffer
BTN3A3 Protein, Human, Recombinant (His)
TMPY-03967
Expression system: HEK293 Cells
Length: 1-248, Extracellular Domain
Activity: Not Tested
Length: 1-248, Extracellular Domain
Activity: Not Tested
- $386
Size
QTY
SPR-compatible buffer
BTNL6 Protein, Mouse, Recombinant (His)
TMPJ-00439
Butyrophilin-like 6 (BTNL6) is a member of the BTN MOG Ig-superfamily and functions with BTNL1 as a regulator of immune cell proliferation. The Btnl6 gene is found only in mice. BTNL6 expression is coordinated as a heteromeric protein with BTNL1, and the presence of this complex is correlated with expansion of gamma δ T cells, especially those containing V gamma 7Vδ4 TCR. Btnl6 shows striking sequence similarity to Skint1; is also largely restricted to an epithelial tissue (the small intestine) replete with T cells. Our in-house studies showed BTNL6 co-inhibited anti-CD3 induced IL-2 secretion on CD3+ cells.
- $163
Size
QTY
BTN3A1 Protein, Human, Recombinant
TMPY-06663
BTN3A1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 24.16 kDa and the accession number is NP_919423.1.
- $801
Size
QTY
SPR-compatible buffer
BTN2A2 Protein, Human, Recombinant (hFc)
TMPJ-01247
Expression system: HEK293 Cells
Length: 33-237, Partial
Activity: Not Tested
Length: 33-237, Partial
Activity: Not Tested
- $184
Size
QTY
SPR-compatible buffer
BTN2A2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPJ-01246
Expression system: HEK293 Cells
Length: 33-237, Partial
Activity: Not Tested
Length: 33-237, Partial
Activity: Not Tested
- $355
Size
QTY
SPR-compatible buffer
BTNL9 Protein, Mouse, Recombinant (hFc)
TMPJ-01209
Expression system: HEK293 Cells
Length: 36-257, Extracellular Domain
Activity: Not Tested
Length: 36-257, Extracellular Domain
Activity: Not Tested
- $147
Size
QTY
SPR-compatible buffer
BTN3A1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPJ-00316
Expression system: HEK293 Cells
Length: 30-254, Extracellular Domain
Activity: Not Tested
Length: 30-254, Extracellular Domain
Activity: Not Tested
- $355
Size
QTY
SPR-compatible buffer
BTN3A1 Protein, Human, Recombinant (E. coli, His)
TMPH-01021
Expression system: E. coli
Length: 30-254, Extracellular Domain
Activity: Not Tested
Length: 30-254, Extracellular Domain
Activity: Not Tested
- $198
Size
QTY
Buffer-exchangeable
BTNL2 Protein, Human, Recombinant (Isoform 4, His)
TMPH-03822
Expression system: E. coli
Length: 28-245, Partial of Isoform 4
Activity: Not Tested
Length: 28-245, Partial of Isoform 4
Activity: Not Tested
- $283
Size
QTY
Buffer-exchangeable
BTNL4 Protein, Mouse, Recombinant (His)
TMPJ-00440
Butyrophilin-like 4, also known as BTLN4, BTN3A3 (human) and BTN3A2 (rat) is an approximately 65 kDa member of the butyrophilin family that may play a role in immune regulation. BTNL4 shows striking sequence similarity to Skint1, is also largely restricted to an epithelial tissue (the small intestine) replete with T cells, plays a role in T-cell responses in the adaptive immune response.
- $143
Size
QTY
SPR-compatible buffer
BTNL9 Protein, Human, Recombinant (hFc)
TMPJ-01194
Expression system: HEK293 Cells
Length: 35-256, Partial
Activity: Not Tested
Length: 35-256, Partial
Activity: Not Tested
- $147
Size
QTY
SPR-compatible buffer
BTNL9 Protein, Human, Recombinant (His)
TMPJ-01195
Expression system: HEK293 Cells
Length: 48-160, Partial
Activity: Not Tested
Length: 48-160, Partial
Activity: Not Tested
- $91
Size
QTY
SPR-compatible buffer
BTN1A1 Protein, Human, Recombinant (His)
TMPY-06542
Expression system: HEK293 Cells
Length: 1-242, Partial
Activity: Not Tested
Length: 1-242, Partial
Activity: Not Tested
- $588
Size
QTY
SPR-compatible buffer
BTN2A2 Protein, Mouse, Recombinant (His)
TMPK-00584
Butyrophilin (BTN) genes encode a set of related proteins. Cell surface BTN2A2 protein, such as the B7 family molecule programmed death ligand 1, was upregulated upon activation of T cells.BTN2A2 is a co-inhibitory molecule that modulates T cell-mediated immunity.
- $418
Size
QTY
SPR-compatible buffer
BTNL2 Protein, Human, Recombinant (Isoform 1, hFc)
TMPH-03821
Expression system: HEK293 Cells
Length: 24-455, Partial
Activity: Not Tested
Length: 24-455, Partial
Activity: Not Tested
- $198
Size
QTY
Buffer-exchangeable
BTNL2 Protein, Mouse, Recombinant (His)
TMPJ-00698
Expression system: HEK293 Cells
Length: 27-452, Partial
Activity: Not Tested
Length: 27-452, Partial
Activity: Not Tested
- $110
Size
QTY
SPR-compatible buffer
BTN3A1 Protein, Human, Recombinant (His), Biotinylated
TMPY-05398
BTN3A1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is O00481-2.
- $383
Size
QTY
SPR-compatible buffer
BTN2A1 Protein, Human, Recombinant (His)
TMPJ-01199
Expression system: HEK293 Cells
Length: 29-248, Extracellular Domain
Activity: Not Tested
Length: 29-248, Extracellular Domain
Activity: Not Tested
- $110
Size
QTY
SPR-compatible buffer
BTN1A1 Protein, Human, Recombinant (hFc)
TMPY-06546
Expression system: HEK293 Cells
Length: 1-242, Partial
Activity: Not Tested
Length: 1-242, Partial
Activity: Not Tested
- $600
Size
QTY
SPR-compatible buffer
BTN1A1 Protein, Mouse, Recombinant (His)
TMPY-06537
Expression system: HEK293 Cells
Length: 1-247, Partial
Activity: Not Tested
Length: 1-247, Partial
Activity: Not Tested
- $600
Size
QTY
SPR-compatible buffer
BTN3A1 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
TMPK-00557
The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7 butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A1 controls activation of human Vγ9 Vδ2 T cells by direct or indirect presentation of self and nonself phosphoantigens (pAg). BTN3A1 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.5 kDa and the accession number is A0A330KWZ1.
- $814
Size
QTY
SPR-compatible buffer
BTN3A1 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00310
Expression system: HEK293 Cells
Length: 30-254, Extracellular Domain
Activity: ELISA
Length: 30-254, Extracellular Domain
Activity: ELISA
- $814
Size
QTY
SPR-compatible buffer
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