Shopping Cart

Your shopping cart is currently empty

Polyquaternium-1

Name: Polyquaternium-1
Brand: TargetMol
SKU: T20655
Price: 47 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

😃Good

Catalog No. T20655Cas No. 75345-27-6

Alias PQ-1, Polidronium chloride

Polyquaternium-1 (PQ-1) exerts strong bacteriostasis and little eye irritation and can be used as a polycationic ophthalmic preservative. Polyquaternium-1 inhibits the growth of microbial contaminants in multi-dose bottles of topical medications.

Polyquaternium-1

Copy Product Info

😃Good

Purity: 95%

Catalog No. T20655Alias PQ-1, Polidronium chlorideCas No. 75345-27-6

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$47	In Stock	In Stock
10 mg	$59	In Stock	In Stock
25 mg	$97	-	In Stock
50 mg	$155	-	In Stock
100 mg	$222	-	In Stock
200 mg	$328	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:95%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR

Product Introduction

Bioactivity

Description	Polyquaternium-1 (PQ-1) exerts strong bacteriostasis and little eye irritation and can be used as a polycationic ophthalmic preservative. Polyquaternium-1 inhibits the growth of microbial contaminants in multi-dose bottles of topical medications.
Synonyms	PQ-1, Polidronium chloride

Chemical Properties

Molecular Weight	556.99
Formula	(C₆H₁₂N)nC₁₆H₃₆N₂O₆Cl₃
Cas No.	75345-27-6
Smiles	[Cl-].[Cl-].[Cl-].C[N+](C)(CC=CC[N+](CCO)(CCO)CCO)CC=CC[N+](CCO)(CCO)CCO \|w:8.5,21.17\|
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 105.00 mg/mL (188.51 mM), Sonication is recommended.

DMSO: < 1 mg/mL (insoluble or slightly soluble)

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	1.7954 mL	8.9768 mL	17.9536 mL	89.7682 mL
5 mM	0.3591 mL	1.7954 mL	3.5907 mL	17.9536 mL
10 mM	0.1795 mL	0.8977 mL	1.7954 mL	8.9768 mL
20 mM	0.0898 mL	0.4488 mL	0.8977 mL	4.4884 mL
50 mM	0.0359 mL	0.1795 mL	0.3591 mL	1.7954 mL
100 mM	0.0180 mL	0.0898 mL	0.1795 mL	0.8977 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc