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Anti-CD28 Antibody-HRP (6Z653) is a HRP-conjugated Mouse antibody targeting CD28. Anti-CD28 Antibody-HRP (6Z653) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | $292 | 7-10 days |
Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Human |
Alias | CD28 molecule |
Ig Type | Mouse IgG1 |
Clone | 6Z653 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 0.1-1 μg/ml |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD28 / TP44 (rh CD28 / TP44; P10747-1Met1-Pro152). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell response pathways. B7/CD28 family members, which can augment or antagonize T-cell receptor signaling, in the regulation of central and peripheral T-cell tolerance. CD28 is thus involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
Conjucates | HRP |
Others Formats | Unconjugated |
Antibody Types Available | 2 |
Immunogen | Recombinant Protein: Human CD28 / TP44 Protein |
Antigen Species | Human |
Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules, Cancer Drug Targets |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
Transport | Shipping with blue ice. |
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