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Complement factor I Protein, Human, Recombinant (His)

Catalog No. TMPK-00776
Synonyms: FIC3b-INA, KAF, IF, CFI, I factor (complement), EC:3.4.21.45, C3B/C4B inactivator, C3BINA

Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Complement factor I Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 487.00
500 μg 5 days $ 1,950.00
1 mg 5 days $ 3,250.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes.
Species Human
Expression System HEK293
Tag C-His
Accession Number P05156
Synonyms FIC3b-INA, KAF, IF, CFI, I factor (complement), EC:3.4.21.45, C3B/C4B inactivator, C3BINA
Construction Recombinant Human Complement factor I Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Lys19-Val583.[Accession |P05156]
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight The protein has a predicted MW of 64.58 kDa. Due to enzyme lysis and glycosylation, the protein migrates to 75-95 kDa based on Tris-Bis PAGE result.
Endotoxin Less than 1EU per μg by the LAL method.
Formulation Lyophilized from 0.22μm filtered solution in 20mM Tris, 150mM NaCl (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability & Storage

-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes.

References and Literature

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Keywords

Complement factor I Protein, Human, Recombinant (His) I factor FIC3b-INA KAF IF CFI complement I factor (complement) EC:3.4.21.45 C3B/C4B inactivator C3BINA recombinant recombinant-proteins proteins protein

 

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