Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CHPG hydrochloride is a selective agonist of mGluR5.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 142.00 | |
5 mg | In stock | $ 329.00 | |
10 mg | In stock | $ 493.00 | |
25 mg | In stock | $ 788.00 | |
50 mg | In stock | $ 1,120.00 | |
100 mg | In stock | $ 1,490.00 | |
500 mg | In stock | $ 2,960.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 286.00 |
Description | CHPG hydrochloride is a selective agonist of mGluR5. |
In vitro | After SO2 derivatives treatment, CHPG hydrochloride (10-500 µM) increases the cell viability and reduces the release of LDH. CHPG hydrochloride (0.5 mM) protects BV2 cells against SO2-induced apoptosis and increases the TSG-6 expression through the TSG-6/NF-κB pathway[1]. |
In vivo | In adult Sprague-Dawley male rats, injection of CHPG hydrochloride (250 nM) reduces significantly cerebral lesion volume by activation of the ERK and Akt signaling pathways[2]. |
Synonyms | CHPG hydrochloride(170846-74-9 Free base) |
Molecular Weight | 238.07 |
Formula | C8H9Cl2NO3 |
CAS No. | T10809L |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (126.01 mM)
You can also refer to dose conversion for different animals. More
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CHPG hydrochloride T10809L MAPK Neuroscience NF-Κb GluR ERK NF-κB CHPG Hydrochloride CHPG hydrochloride(170846-74-9 Free base) inhibitor inhibit