Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Benzyl-PEG12-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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Description | Benzyl-PEG12-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Synonyms | Benzyl-PEG12-alcohol |
Molecular Weight | 636.776 |
Formula | C31H56O13 |
CAS No. | 2218463-17-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Benzyl-PEG12-alcohol 2218463-17-1 Benzyl PEG12 alcohol BenzylPEG12alcohol Benzyl-PEG-12-alcohol inhibitor inhibit