PKG Substrate

Name: PKG Substrate
Brand: TargetMol
SKU: TP1787
Rating: 4.5 (1 reviews)

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Catalog No. TP1787Cas No. 81187-14-6

PKG Substrate is a selective substrate for cGMP-dependent protein kinase (PKG), showing a strong preference for PKG Iα (Km = 59 µM) over PKG II (Km = 305 µM).

PKG Substrate

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Catalog No. TP1787Cas No. 81187-14-6

PKG Substrate is a selective substrate for cGMP-dependent protein kinase (PKG), showing a strong preference for PKG Iα (Km = 59 µM) over PKG II (Km = 305 µM).

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$90	Inquiry	Inquiry
5 mg	$319	Inquiry	Inquiry

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Product Introduction

Bioactivity

Description

PKG Substrate is a selective substrate for cGMP-dependent protein kinase (PKG), showing a strong preference for PKG Iα (Km = 59 µM) over PKG II (Km = 305 µM).

Chemical Properties

Molecular Weight	902.01
Formula	C₃₅H₆₇N₁₇O₁₁
Cas No.	81187-14-6
Smiles	[C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CCCCN)=O)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCC(O)=O)C(O)=O)=O)C)=O)CCCNC(=N)N)=O)CO)=O)CCCNC(=N)N
Relative Density.	1.55 g/cm3 (Predicted)
Sequence	Arg-Lys-Arg-Ser-Arg-Ala-Glu
Sequence Short	RKRSRAE

Storage & Solubility Information

Storage	keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	H2O: Soluble

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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