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Anti-NGF Antibody (1J940) is a Rabbit antibody targeting NGF. Anti-NGF Antibody (1J940) can be used in IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-NGF Antibody (1J940) is a Rabbit antibody targeting NGF. Anti-NGF Antibody (1J940) can be used in IHC-P. |
Alias | Ngfb, nerve growth factor (β polypeptide), nerve growth factor (beta polypeptide) |
Ig Type | Monoclonal Rabbit IgG |
Clone | 1J940 |
Reactivity | Human |
Verified Activity | Immunochemical staining of human β-NGF in human brain (from 2 donors) with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
Application | IHC-P |
Recommended Dose | IHC-P: 1:100-1:500 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human NGF / NGFB (rh NGF / NGFB; TMPY-01010; NP_002497.2; Ser122-Arg239). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF (beta-NGF), was demonstrated to exhibits the growth-stimulating activity of NGF protein. NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein that homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. Also, previous studies indicated that NGF may also have an important role in the regulation of the immune system. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human NGF / NGFB protein (TMPY-01010) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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