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Anti-TIMP-1 Antibody (9P220) is a Mouse antibody targeting TIMP-1. Anti-TIMP-1 Antibody (9P220) can be used in ELISA, IHC.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μg | $207 | 7-10 days | |
100 μg | $348 | 7-10 days |
Description | Antibody Type: Mouse Monoclonal Application: ELISA, IHC Reactivity: Rat |
Alias | Tissue inhibitor of metalloproteinases 1, Timp1, Metalloproteinase inhibitor 1 |
Ig Type | IgG1 |
Clone | 9P220 |
Reactivity | Rat |
Verified Activity | Immunohistochemistry of paraffin-embedded Rat prostate cancer using TMAH-01174 at dilution of 1:100. |
Application | ELISA, IHC |
Antibody Type | Monoclonal |
Host Species | Mouse |
Subcellular Localization | Secreted. |
Construction | Hybridoma Monoclonal Antibody |
Purification | Protein G purified |
Appearance | Liquid |
Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
Purity | >95% |
Research Background | Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Also stimulates steroidogenesis by Leydig and ovarian granuloma cells; procathepsin L is required for maximal activity. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: Rat Timp1 |
Antigen Species | Rat |
Gene ID | 116510 |
Uniprot ID | |
Biology Area | Cardiovascular |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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