Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PRI-724 (C-82 prodrug) is a selective small-molecule inhibitor of β-catenin/CBP interaction.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 116.00 | |
5 mg | In stock | $ 248.00 | |
10 mg | In stock | $ 397.00 | |
25 mg | In stock | $ 663.00 | |
50 mg | In stock | $ 945.00 | |
100 mg | In stock | $ 1,280.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 297.00 |
Description | PRI-724 (C-82 prodrug) is a selective small-molecule inhibitor of β-catenin/CBP interaction. |
In vivo | PRI-724 reduces liver fibrosis, and hepatic hydroxyproline levels, in HCV mice while attenuating αSMA induction. PRI-724 increased the levels of matrix metalloproteinase (MMP)-8 mRNA in the liver, along with elevated levels of intrahepatic neutrophils and macrophages/monocytes. In conclusion, PRI-724 ameliorates HCV-induced liver fibrosis in mice. PRI-724 is a drug candidate which possesses antifibrotic effect[1]. |
Synonyms | C-82 prodrug, Foscenvivint |
Molecular Weight | 658.64 |
Formula | C33H35N6O7P |
CAS No. | 1422253-38-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90.0 mg/mL (136.6 mM)
Ethanol: 1.8 mg/mL (2.7 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PRI-724 1422253-38-0 Cytoskeletal Signaling Stem Cells Wnt/beta-catenin C-82 prodrug PRI724 Foscenvivint PRI 724 inhibitor inhibit