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Anti-Phospho-CCND1 (Thr286) Polyclonal Antibody
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Catalog No. TMAC-01038
Alias p-CCND1 (Thr286), p-CCND1 (T286), CCND1 (p-Thr286), CCND1 (p-T286)
Anti-Phospho-CCND1 (Thr286) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CCND1 (Thr286). Anti-Phospho-CCND1 (Thr286) Polyclonal Antibody can be used in WB.
Anti-Phospho-CCND1 (Thr286) Polyclonal Antibody
Anti-Phospho-CCND1 (Thr286) Polyclonal Antibody
😃Good
Catalog No. TMAC-01038Alias p-CCND1 (Thr286), p-CCND1 (T286), CCND1 (p-Thr286), CCND1 (p-T286)
Anti-Phospho-CCND1 (Thr286) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CCND1 (Thr286). Anti-Phospho-CCND1 (Thr286) Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $217 | 7-10 days | 7-10 days | |
| 100 μL | $316 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Phospho-CCND1 (Thr286) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CCND1 (Thr286). Anti-Phospho-CCND1 (Thr286) Polyclonal Antibody can be used in WB. |
| Synonyms | p-CCND1 (Thr286), p-CCND1 (T286), CCND1 (p-Thr286), CCND1 (p-T286) |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of extracts from MCF7 tissue using Cyclin D1 (Phospho-Thr286) antibody TMAC-01038. The lane on the right is treated with the antigen-specific peptide.  |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1. Ubiquitinates STUB1-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of threonine 286 (A-C-T(p)-P-T) derived from Human Cyclin D1 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 33 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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