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L-Valyl-L-phenylalanine

Name: L-Valyl-L-phenylalanine
Brand: TargetMol
SKU: T19402
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: Valylphenylalanine, H-VAL-PHE-OH) Copy Product Info

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Synonyms: Valylphenylalanine, H-VAL-PHE-OH

Catalog No. T19402 Copy Product Info

Purity: 99.73%

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L-Valyl-L-phenylalanine is a dipeptide formed by the linkage of valine and phenylalanine via a peptide bond. It exhibits good biocompatibility and can be used in research on targeted drug delivery. L-Valyl-L-phenylalanine possesses hydrophobic side chains, and the dipeptide alkyl esters derived from it can be used to deplete cytotoxic T lymphocytes or natural killer cells from living organisms, cell populations, or tissues, making them useful for research into graft-versus-host disease (GVHD).

Cas No. 3918-92-1

Pack Size	Price	USA Stock	Global Stock	Quantity
100 mg	$30	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.73%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	L-Valyl-L-phenylalanine is a dipeptide formed by the linkage of valine and phenylalanine via a peptide bond. It exhibits good biocompatibility and can be used in research on targeted drug delivery. L-Valyl-L-phenylalanine possesses hydrophobic side chains, and the dipeptide alkyl esters derived from it can be used to deplete cytotoxic T lymphocytes or natural killer cells from living organisms, cell populations, or tissues, making them useful for research into graft-versus-host disease (GVHD).
In vitro	An alkyl ester of dipeptide composed of L-valyl-L-phenylalanine can be used to eliminate cytotoxic T lymphocytes or natural killer cells in organisms, cell cultures, or tissues [1].
Synonyms	Valylphenylalanine, H-VAL-PHE-OH

Chemical Properties

Molecular Weight	264.32
Formula	C₁₄H₂₀N₂O₃
Cas No.	3918-92-1
Smiles	[C@@H](CC1=CC=CC=C1)(NC([C@H](C(C)C)N)=O)C(O)=O
Relative Density.	1.166g/cm3
Sequence	Val-Phe
Sequence Short	VF

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 53.34 mg/mL (201.8 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	3.7833 mL	18.9165 mL	37.8329 mL	189.1646 mL
5 mM	0.7567 mL	3.7833 mL	7.5666 mL	37.8329 mL
10 mM	0.3783 mL	1.8916 mL	3.7833 mL	18.9165 mL
20 mM	0.1892 mL	0.9458 mL	1.8916 mL	9.4582 mL
50 mM	0.0757 mL	0.3783 mL	0.7567 mL	3.7833 mL
100 mM	0.0378 mL	0.1892 mL	0.3783 mL	1.8916 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

L-Valyl-L-phenylalanineLValylLphenylalanineL Valyl L phenylalanineHuman Endogenous Metabolite

Related Tags: L-Valyl-L-phenylalanine chemical structure | L-Valyl-L-phenylalanine in vitro | L-Valyl-L-phenylalanine formula | L-Valyl-L-phenylalanine molecular weight