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IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi), Biotinylated

Catalog No. TMPK-00333
Synonyms: IL-1 Rrp2, IL-1 R6, IL1RL2, IL1RRP2, IL-36R

IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 39.1 kDa and the accession number is Q9HB29-1.

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IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi), Biotinylated
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 814.00
500 μg 5 days $ 3,250.00
1 mg 5 days $ 5,440.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 39.1 kDa and the accession number is Q9HB29-1.
Species Human
Expression System HEK293 Cells
Tag C-His-Avi
Accession Number Q9HB29-1
Synonyms IL-1 Rrp2, IL-1 R6, IL1RL2, IL1RRP2, IL-36R
Construction Asp20-Arg335
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight 39.1 kDa (predicted). Due to glycosylation, the protein migrates to 55-75 kDa based on Tris-Bis PAGE result.
Endotoxin < 1 EU/μg by the LAL method.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice.

Research Background The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). IL1RL2 is a receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways.

References and Literature

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Keywords

IL-1 Rrp2/IL-1 R6 Protein, Human, Recombinant (His & Avi), Biotinylated IL-1 Rrp2 IL-1 R6 IL1RL2 IL1RRP2 IL-36R recombinant recombinant-proteins proteins protein

 

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