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Anti-Alkaline Phosphatase/ALPL Antibody (2T822)
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Catalog No. TMAY-02547
Alias TNSALP, TNAP, HOPS, AP-TNAP, APTNAP, alkaline phosphatase, liver/bone/kidney
Anti-Alkaline Phosphatase/ALPL Antibody (2T822) is a Rabbit antibody targeting Alkaline Phosphatase/ALPL. Anti-Alkaline Phosphatase/ALPL Antibody (2T822) can be used in ELISA.
Anti-Alkaline Phosphatase/ALPL Antibody (2T822)
Anti-Alkaline Phosphatase/ALPL Antibody (2T822)
😃Good
Catalog No. TMAY-02547Alias TNSALP, TNAP, HOPS, AP-TNAP, APTNAP, alkaline phosphatase, liver/bone/kidney
Anti-Alkaline Phosphatase/ALPL Antibody (2T822) is a Rabbit antibody targeting Alkaline Phosphatase/ALPL. Anti-Alkaline Phosphatase/ALPL Antibody (2T822) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
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Product Introduction
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Chemical Properties
| Description | Anti-Alkaline Phosphatase/ALPL Antibody (2T822) is a Rabbit antibody targeting Alkaline Phosphatase/ALPL. Anti-Alkaline Phosphatase/ALPL Antibody (2T822) can be used in ELISA. |
| Synonyms | TNSALP, TNAP, HOPS, AP-TNAP, APTNAP, alkaline phosphatase, liver/bone/kidney |
| Ig Type | Rabbit IgG |
| Clone | 2T822 |
| Reactivity | Human |
| Specificity | Human Alkaline phosphatase/APLI No cross-reactivity in ELISA with Human ALPL |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human ALPI (rh ALPI; TMPY-02650; P09923; Met1-Asp503). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | ALPI encodes for intestinal phosphatase alkaline, a brush border metalloenzyme that hydrolyses phosphate from the lipid A moiety of lipopolysaccharides and thereby drastically reduces Toll-like receptor 4 agonist activity. ALPI mutations impaired either stability or catalytic activity of ALPI and rendered it unable to detoxify lipopolysaccharide-dependent signalling. ALPI mutations should be included in screening for monogenic causes of inflammatory bowel diseases and lay the groundwork for ALPI-based treatments in intestinal inflammatory disorders. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human ALPI protein (TMPY-02650) |
| Antigen Species | Human |
| Biology Area | Phosphatases and Regulators |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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