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Anti-Alkaline Phosphatase/ALPL Antibody (2T822) is a Rabbit antibody targeting Alkaline Phosphatase/ALPL. Anti-Alkaline Phosphatase/ALPL Antibody (2T822) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $268 | 7-10 days |
Description | Anti-Alkaline Phosphatase/ALPL Antibody (2T822) is a Rabbit antibody targeting Alkaline Phosphatase/ALPL. Anti-Alkaline Phosphatase/ALPL Antibody (2T822) can be used in ELISA. |
Alias | TNSALP, TNAP, HOPS, AP-TNAP, APTNAP, alkaline phosphatase, liver/bone/kidney |
Ig Type | Monoclonal Rabbit IgG |
Clone | 2T822 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human ALPI (rh ALPI; TMPY-02650; P09923; Met1-Asp503). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | ALPI encodes for intestinal phosphatase alkaline, a brush border metalloenzyme that hydrolyses phosphate from the lipid A moiety of lipopolysaccharides and thereby drastically reduces Toll-like receptor 4 agonist activity. ALPI mutations impaired either stability or catalytic activity of ALPI and rendered it unable to detoxify lipopolysaccharide-dependent signalling. ALPI mutations should be included in screening for monogenic causes of inflammatory bowel diseases and lay the groundwork for ALPI-based treatments in intestinal inflammatory disorders. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human ALPI protein (TMPY-02650) |
Antigen Species | Human |
Biology Area | Phosphatases and Regulators |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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