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Anti-Alkaline Phosphatase/ALPL Antibody (2T822)

😃Good
Catalog No. TMAY-02547
Alias TNSALP, TNAP, HOPS, AP-TNAP, APTNAP, alkaline phosphatase, liver/bone/kidney

Anti-Alkaline Phosphatase/ALPL Antibody (2T822) is a Rabbit antibody targeting Alkaline Phosphatase/ALPL. Anti-Alkaline Phosphatase/ALPL Antibody (2T822) can be used in ELISA.

Anti-Alkaline Phosphatase/ALPL Antibody (2T822)

Anti-Alkaline Phosphatase/ALPL Antibody (2T822)

😃Good
Catalog No. TMAY-02547Alias TNSALP, TNAP, HOPS, AP-TNAP, APTNAP, alkaline phosphatase, liver/bone/kidney
Anti-Alkaline Phosphatase/ALPL Antibody (2T822) is a Rabbit antibody targeting Alkaline Phosphatase/ALPL. Anti-Alkaline Phosphatase/ALPL Antibody (2T822) can be used in ELISA.
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100 μL$268 7-10 days
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Product Introduction

Bioactivity
Description
Anti-Alkaline Phosphatase/ALPL Antibody (2T822) is a Rabbit antibody targeting Alkaline Phosphatase/ALPL. Anti-Alkaline Phosphatase/ALPL Antibody (2T822) can be used in ELISA.
AliasTNSALP, TNAP, HOPS, AP-TNAP, APTNAP, alkaline phosphatase, liver/bone/kidney
Ig Type
Monoclonal Rabbit IgG
Clone
2T822
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human ALPI (rh ALPI; TMPY-02650; P09923; Met1-Asp503).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundALPI encodes for intestinal phosphatase alkaline, a brush border metalloenzyme that hydrolyses phosphate from the lipid A moiety of lipopolysaccharides and thereby drastically reduces Toll-like receptor 4 agonist activity. ALPI mutations impaired either stability or catalytic activity of ALPI and rendered it unable to detoxify lipopolysaccharide-dependent signalling. ALPI mutations should be included in screening for monogenic causes of inflammatory bowel diseases and lay the groundwork for ALPI-based treatments in intestinal inflammatory disorders.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human ALPI protein (TMPY-02650)
Antigen Species
Human
Biology Area
Phosphatases and Regulators
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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