Popular Searches
Diphenyleneiodonium chlorideEpacadostatGilteritinibDinaciclibRo-3306
TargetMol | Star Product
Wikimole
TargetMol | New Product
New Product
TargetMol | Compound Library
Compound Library
Contact UsQuotation
Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPRelated productsBioactivityChemical infoStorage&SolubilityCalculator

2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

😃Good
Catalog No. T35652Cas No. 146877-98-7

2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis. In addition, dGMP can be efficiently phosphorylated by the type I thymidylate kinase of the malarial agent P. falciparum. In humans, deficiency of mitochondrial deoxyguanosine kinase, which synthesizes dGMP from ATP and deoxyguanosine, contributes to mitochondrial DNA depletion syndrome.

2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
Other Forms of 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate):
2'-Deoxyguanosine 5'-monophosphate disodiumT3763633430-61-4
In Stock
View details

2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

😃Good
Catalog No. T35652Cas No. 146877-98-7
2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis. In addition, dGMP can be efficiently phosphorylated by the type I thymidylate kinase of the malarial agent P. falciparum. In humans, deficiency of mitochondrial deoxyguanosine kinase, which synthesizes dGMP from ATP and deoxyguanosine, contributes to mitochondrial DNA depletion syndrome.
Pack SizePriceAvailabilityQuantity
500 mg$17835 days
1 g$27935 days
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View More

Resource Download

Product Introduction

Bioactivity
Description
2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis. In addition, dGMP can be efficiently phosphorylated by the type I thymidylate kinase of the malarial agent P. falciparum. In humans, deficiency of mitochondrial deoxyguanosine kinase, which synthesizes dGMP from ATP and deoxyguanosine, contributes to mitochondrial DNA depletion syndrome.
Chemical Properties
Molecular Weight409.202
FormulaC10H14N5Na2O8P
Cas No.146877-98-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
PBS (pH 7.2): 10 mg/mL (24.44 mM), Sonication is recommended.
Solution Preparation Table
PBS (pH 7.2)
1mg5mg10mg50mg
1 mM2.4438 mL12.2189 mL24.4378 mL122.1890 mL
5 mM0.4888 mL2.4438 mL4.8876 mL24.4378 mL
10 mM0.2444 mL1.2219 mL2.4438 mL12.2189 mL
20 mM0.1222 mL0.6109 mL1.2219 mL6.1095 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

2'Deoxyguanosine 5'monophosphate (sodium salt hydrate)sodium Hydrate2'-Deoxyguanosine 5'-monophosphate2' Deoxyguanosine 5' monophosphate (sodium salt hydrate)
Related Tags: buy 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate) | purchase 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate) | 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate) cost | order 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate) | 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate) chemical structure | 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate) formula | 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate) molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.