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Saikosaponin D

Name: Saikosaponin D
Brand: TargetMol
SKU: T3913
Price: 47 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3913Cas No. 20874-52-6

Saikosaponin D is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity.

Saikosaponin D

🥰Excellent

Purity: 99.73%

Catalog No. T3913Cas No. 20874-52-6

Saikosaponin D is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity.

Pack Size	Price	Availability
5 mg	$47	In Stock
10 mg	$72	In Stock
25 mg	$147	In Stock
50 mg	$239	In Stock
100 mg	$428	In Stock
1 mL x 10 mM (in DMSO)	$61	In Stock

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Batch Information

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Purity:99.73%

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Product Introduction

Bioactivity

Description

Saikosaponin D is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity.

Chemical Properties

Molecular Weight	780.98
Formula	C₄₂H₆₈O₁₃
Cas No.	20874-52-6
Smiles	CC1OC(OC2CCC3(C)C(CCC4(C)C3C=CC35OCC6(CCC(C)(C)CC36)C(O)CC45C)C2(C)CO)C(O)C(OC2OC(CO)C(O)C(O)C2O)C1O
Relative Density.	1.36 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 262 mg/mL (335.48 mM), Sonication is recommended.

H2O: insoluble

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2804 mL	6.4022 mL	12.8044 mL	64.0221 mL
5 mM	0.2561 mL	1.2804 mL	2.5609 mL	12.8044 mL
10 mM	0.1280 mL	0.6402 mL	1.2804 mL	6.4022 mL
20 mM	0.0640 mL	0.3201 mL	0.6402 mL	3.2011 mL
50 mM	0.0256 mL	0.1280 mL	0.2561 mL	1.2804 mL
100 mM	0.0128 mL	0.0640 mL	0.1280 mL	0.6402 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc