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Anti-PRLR Antibody (2J629) is an antibody targeting PRLR. Anti-PRLR Antibody (2J629) can be used in ELISA, IHC.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $208 | 7-10 days | |
100 μL | $349 | 7-10 days |
Description | Anti-PRLR Antibody (2J629) is an antibody targeting PRLR. Anti-PRLR Antibody (2J629) can be used in ELISA, IHC. |
Alias | prolactin receptor, PRLR, MFAB, hPRLrI, HPRL |
Ig Type | hIgG1 |
Clone | 2J629 |
Reactivity | Human |
Verified Activity | IHC image of TMAH-01007 diluted at 1:200 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB. |
Application | ELISA, IHC |
Recommended Dose | IHC:1:50-1:200. |
Antibody Type | Monoclonal |
Subcellular Localization | Membrane; Single-pass type I membrane protein.; [Isoform 7]: Secreted. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
Research Background | This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: Human PRLR Protein |
Antigen Species | Human |
Gene ID | |
Uniprot ID | |
Biology Area | Cancer, Metabolism, Signal transduction |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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