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IL-1 beta/IL-1F2 Protein, Cavia porcellus, Recombinant (His)

(Synonyms: Interleukin-1 β, Interleukin-1 beta, IL1B, IL-1 β, IL-1 beta) Copy Product Info

Synonyms: Interleukin-1 β, Interleukin-1 beta, IL1B, IL-1 β, IL-1 beta

Catalog No. TMPJ-01392 Copy Product Info
Interleukin-1 beta (IL1B) belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and is reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$8035 days35 days
10 μg$12935 days35 days
20 μg$19835 days35 days
50 μg$39035 days35 days
100 μg$62635 days35 days
200 μg$98735 days35 days
500 μg$1,90035 days35 days
1 mg$2,73035 days35 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Interleukin-1 beta (IL1B) belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and is reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Species
Cavia porcellus
Expression System
E. coli
TagC-6xHis
Accession NumberQ9WVG1
Amino AcidThr115-Ser266
ConstructionThr115-Ser266
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsInterleukin-1 β, Interleukin-1 beta, IL1B, IL-1 β, IL-1 beta
Research Background
Chemical Properties
Molecular Weight16-19 KDa (reducing condition)
Storage & Solubility Information
StorageLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Related Tags: IL-1 beta/IL-1F2 Protein, Cavia porcellus, Recombinant (His) chemical structure | IL-1 beta/IL-1F2 Protein, Cavia porcellus, Recombinant (His) molecular weight