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PLN-1474

Name: PLN-1474
Brand: TargetMol
SKU: T60101
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T60101Cas No. 2408065-32-5

Alias PLN1474

PLN-1474 is a potent αVβ1 inhibitor with IC50 < 50 nM.

PLN-1474

🥰Excellent

Purity: 99.92%

Catalog No. T60101Alias PLN1474Cas No. 2408065-32-5

PLN-1474 is a potent αVβ1 inhibitor with IC50 < 50 nM.

Pack Size	Price	Availability
1 mg	$48	In Stock
5 mg	$113	In Stock
10 mg	$189	In Stock
25 mg	$322	In Stock
50 mg	$463	In Stock
100 mg	$645	In Stock
1 mL x 10 mM (in DMSO)	$126	In Stock

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Batch Information

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Purity:99.92%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	PLN-1474 is a potent αVβ1 inhibitor with IC50 < 50 nM.
Synonyms	PLN1474

Chemical Properties

Molecular Weight	431.57
Formula	C₂₄H₃₇N₃O₄
Cas No.	2408065-32-5
Smiles	CC1(CCOCC1)C(=O)N[C@@H](CCCCCCCC1=CC=C2CCCN=C2N1)C(O)=O
Relative Density.	1.23 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (115.86 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3171 mL	11.5856 mL	23.1712 mL	115.8561 mL
5 mM	0.4634 mL	2.3171 mL	4.6342 mL	23.1712 mL
10 mM	0.2317 mL	1.1586 mL	2.3171 mL	11.5856 mL
20 mM	0.1159 mL	0.5793 mL	1.1586 mL	5.7928 mL
50 mM	0.0463 mL	0.2317 mL	0.4634 mL	2.3171 mL
100 mM	0.0232 mL	0.1159 mL	0.2317 mL	1.1586 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc