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Anti-PTPN11 Antibody (3Q313) (Synonyms: SH-PTP 3, Shp2))

Catalog No. TMAC-03748 Copy Product Info
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Anti-PTPN11 Antibody (3Q313) is a Rabbit antibody targeting PTPN11. Anti-PTPN11 Antibody (3Q313) can be used in IP,WB.

Anti-PTPN11 Antibody (3Q313)

Copy Product Info
🥰Excellent
Catalog No. TMAC-03748
Synonyms SH-PTP 3, Shp2)

Anti-PTPN11 Antibody (3Q313) is a Rabbit antibody targeting PTPN11. Anti-PTPN11 Antibody (3Q313) can be used in IP,WB.

Anti-PTPN11 Antibody
(3Q313)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PTPN11 Antibody (3Q313) is a Rabbit antibody targeting PTPN11. Anti-PTPN11 Antibody (3Q313) can be used in IP,WB.
SynonymsSH-PTP 3, Shp2)
Ig Type
IgG
Clone
3Q313
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-5000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs). Several groups have independently identified a non-transmembrane PTP, designated SH-PTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N-terminal to the PTP domain. SH2 domains generally mediate the association of regulatory molecules with specific phosphotyrosine-containing sites on autophosphorylated receptors, thereby controlling the initial interaction of receptors with these substrates. A second and much more widely expressed PTP with SH2 domains, SH-PTP2 (also designated PTP1D and Syp), has been identified. Strong sequence similarity between SH-PTP2 and the Drosophila gene corkscrew (CSW) and their similar patterns of expression suggest that SH-PTP2 is the human corkscrew homolog.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 68 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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