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Anti-infection

Anti-infective is a general term that encompasses antibiotics, antifungals, antiprotozoans and antivirals.

  • Vincetoxicoside B
    TN111322007-72-3
    Vincetoxicoside B, isolated from Polygonum paleaceum Wall. Vincetoxicoside B , quercetin, kaempferol , and (-)-epicatechin show synergistic antifungal activities with the FICI values <0.5.
    • $45
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  • Pyrolin
    TN487195-71-6
    Pyrolin has a strong antifungal activity and exerts a potent impact on the ultrastructure of M.fructicola.
    • $29
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  • α-Terpineol
    Fr1411598-55-5
    Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.
    • $31
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  • Octacosanoic acid
    T8121506-48-9
    Octacosanoic acid has antiplatelet and antithrombotic effects.
    • $66
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  • 2-Furoic acid
    T554488-14-2
    2-Furoic acid (Furan-2-carboxylic acid) 2-Furoic acid can reduce serum cholesterol and triglyceride levels and has anti-lipidemic effects.
    • $41
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  • Monocaprin
    T96022277-23-8
    Monocaprin is a 1-monoglyceride of capric acid that has antimicrobial activity against enveloped viruses, certain bacteria, and the yeast Candida albicans.
    • $52
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  • 5-Geranoxy-7-methoxycoumarin
    TN31107380-39-4
    5-Geranoxy-7-methoxycoumarin shows antifungal activity.
    • $106
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  • Isoforsythiaside
    T3S10881357910-26-9
    Isoforsythiaside has antioxidant, and antibacterial activities.
    • $58
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  • N-(Hydroxymethyl)nicotinamide
    T78693569-99-1
    N-(Hydroxymethyl)nicotinamide (Bilamid) is an antimicrobial agent.
    • $41
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  • pimpinellin
    T5776131-12-4
    Pimpinellin is a natural product that acts as antagonist of proteins with GABA receptor activity.
    • $89
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  • Delamanid
    T4202681492-22-8
    Delamanid (OPC-67683) is an anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid synthesis of bacterial cell wall.
    • $39
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  • 4-Acetamidobenzenesulfonamide
    T8627121-61-9
    4-Acetamidobenzenesulfonamide used in proteomics research and is an anti-infective agent
    • $41
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  • Eriodictyol chalcone
    TN398714917-41-0
    Eriodictyol chalcone has anti-plasmodial effects on P. falciparum growth.
    • $290
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  • 8-Epidiosbulbin E acetate
    TN134291095-48-6
    8-Epidiosbulbin E acetate exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria, including vancomycin-resistant enterococci.
    • $91
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  • 3,4,5-Trimethoxybenzaldehyde
    T959986-81-7
    3,4,5-Trimethoxybenzaldehyde shows anti-Candida efficacy and inhibits adhesion and biofilms.
    • $41
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  • Fuziline
    T3S063180665-72-1
    Fuziline is a diterpene alkaloid found in Aconitum kusnezoffii and Aconitum carmichaelii.It is functionally related to an aconitane.
    • $97
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  • Sulfabrom
    T16952116-45-0
    Sulfabrom (Sulfabromomethazine) is a long-acting sulfonamide medicine for the treatment of coccidiosis and various bacterial infections in poultry, pigs, and cattle.
    • $31
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  • 2'-Hydroxy-4'-methylacetophenone
    Fr142986921-64-8
    2'-Hydroxy-4'-methylacetophenone, a phenolic compound isolated from Angelicae koreana roots possesses acaricidal property. 2'-Hydroxy-4'-methylacetophenone has acaricidal activity, it could be used in the preparation of 4'-methyl-2'-[(p-tolylsulfonyl) oxy] acetophenone.
    • $29
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  • 2-Desoxy-4-epi-pulchellin
    TN2755122872-03-1
    2-Desoxy-4-epi-pulchellin has potent in vitro cytotoxicities against the K562, MCF-7, Hela, DU145, U937, H1975, SGC-7901, A549, MOLT-4, and HL60 cell lines with IC50 values ranging from 0.10 to 46.7uM, while it shows significant antiviral (H1N1 and H3N2) activities, it also displays significant antimycobacterial activity (IC50=7.6 uM).
    • $122
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  • Secoxyloganin
    T3S153458822-47-2
    Secoxyloganin possesses a hepato-protective effect. Secoxyloganin possesses antibacterial activity. Secoxyloganin has cytotoxic activity against UACC-62 cell line.Secoxyloganin possesses the perfect protective effect on PRRSV infected cell and with the minimum protection concentration of 6. 25 μg/mL.
    • $130
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  • Febrifugine
    TN101224159-07-7
    Febrifugine is an effective coccidiostat, possesses schizonticide props; it and its derivatives shows high degree of antimalarial activity but use limited by toxicity .
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    • Baicalin methyl ester
      TN142782475-03-4
      Baicalin methyl ester shows inhibitory effects on the Avian Myeloblastosis Virus reverse transcriptase (AMV-RT).
      • $50
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    • Kaempferol 3-O-sophoroside
      TN110819895-95-5
      Kaempferol 3-O-sophoroside (Kaempferol 3-O-beta-sophoroside) has antibacterial and antiviral activities.
      • $76
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    • paulownin
      T569113040-46-5
      Paulownin, a furofuran lignan from Paulownia tomentosa,has the action of anti-inflammation,analgesia,immunity,hypoglycemia and has little toxicity.
      • $64
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    • Heraclenin
      TL00132880-49-1
      Heraclenin has anticoagulant, and anti-inflammatory activities, it also has mutagenicity in Chlamydomonas reinhardii. Heraclenin can induce apoptosis in Jurkat leukemia cells, it has a strong clastogenic effect . (+)-Heraclenin displays significant levels
      • $68
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    • Pyromeconic acid
      TL0015496-63-9
      Pyromeconic acid (3-hydroxy-4H-pyran-4-one) and derivatives thereof are potent inhibitors of endonuclease
      • $50
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    • Viridicatol
      T1330514484-44-7
      Viridicatol, with potent antibacterial activity against Staphylococcus aureus(MIC: 15.6 μg/mL), is isolated from the fermentation of an endophytic fungus Penicillium sp. R22 in Nerium indicum.
      • $77
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    • Ceftezole sodium
      T785841136-22-5
      Ceftezole sodium (Falomesin) is a broad-spectrum cephalosporin antibiotic active gram-negative and gram-positive bacteria except for Proteus vulgaris, Pseudomonas aeruginosa, and Serratia marcescens. It has the inhibition of cell wall synthesis via affinity for penicillin-binding proteins. It also inhibits alpha-glucosidase.
      • $29
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    • Antibacterial agent 27 
      T961265795-51-9
      Antibacterial agent 27 has potent anti-Candida activity.
      • $74
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    • Robinetin
      TN2158490-31-3
      Robinetin (3,3',4',5',7-Pentahydroxyflavone) has antioxidant and antiradical activities, inhibits EYPC membrane lipid peroxidation and HbA glycosylation with high efficiency.
      • $43
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    • Rubiadin-1-methyl ether
      T42377460-43-7
      Rubiadin-1-methyl ether (Rubiadin 1-methyl ether) is a natural product.It inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nuclear translocation of p65.
      • $40
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    • (+)-Aromadendrene
      T8247489-39-4
      (+)-Aromadendrene is a natural product that has significant antibacterial activity against the Gram-positive and Gram-negative bacteria.
      • $81
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    • Niranthin
      TN466050656-77-4
      Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competitive inhibitor interacting with both subunits of the enzyme. Niranthin also exhibits anti-hepatitis B virus, antiinflammatory and antiallodynic actions.
      • $198
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    • Evocarpine
      TN112115266-38-3
      Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels.
      • $83
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    • Bacopasaponin C
      TN1432178064-13-6
      Bacopasaponin C may have antioxidant activity, it also shows anti-leishmanial property.
      • $68
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    • SulfadiMethoxine sodium
      T81331037-50-9
      Sulfadimethoxine is a antimicrobial agent, treatment of respiratory, urinary tract, enteric, and soft tissue infections
      • $58
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    • Piperlonguminine
      TN20855950-12-9
      Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibacterial activities.Piperlonguminine is an inhibitor of Akt/mTOR signalling. It acts by promoting autophagy and mediating cancer cell death.
      • $52
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    • Dictamine
      T5746484-29-7
      Dictamine (Dectamine) shows anticholinesterase, anti-inflammatory, mutagenic, and has antimicrobial activity against bacteria and fungi. It has the ability to exert cytotoxicity in human cervix, colon, and oral carcinoma cells.
      • $82
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    • Octahydrocurcumin
      T3S169236062-07-4
      Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechanism of inhibiting NF-kB translocation to the nucleus. Octahydrocurcumin exhibits potent cytotoxic effect (IC50 =19.46 ug/mL) and shows high antimicrobial activity.
      • $42
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    • 1,3,5,8-Tetrahydroxyxanthone
      TN10842980-32-7
      1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Gentianella acuta. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity. Dimethylbellidifolin shows mutagenicity in Salmonella typhimurium TA100, TA98, TA97, and TA2637 by the preincubation method; it also exhibits at the dose of 200 ug/disk a significant inhibition of the growth of Staphylococcus aureus.
      • $89
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    • Methyl rosmarinate
      TN192899353-00-1
      Methyl rosmarinate is a noncompetitive tyrosinase inhibitor which is isolated from Rabdosia serra, with an IC50 of 0.28 mM for mushroom tyrosinase.Methyl rosmarinate shows antioxidative, and antifungal activities. It has inhibitory activities against tyrosinase, α±-glucosidase, and matrix metalloproteinase-1 (MMP-1).
      • $68
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    • Dihydropinosylvin
      TN386114531-52-3
      Dihydropinosylvinin is an phytoalexin, it shows antifungal activity against Cladosporium cladosporioides, Botryodiplodia theobromae, Aspergillus niger and Penicillium schlerotgenum, it also exhibits strong antibacterial activity against Bacillus cereus, S
      • $85
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    • Quercimeritrin
      TN1041491-50-9
      Quercimeritrin (Quercetin-7-O-beta-D-glucopyranoside) has antibacterial activity, it shows promising activity against Staphylococcus aureus.
      • $39
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    • 7-Hydroxyflavanone
      T79996515-36-2
      7-Hydroxyflavanone shows antimicrobial activity against Streptococcus pneumoniae clinical isolates.
      • $83
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    • Sorbic acid
      T8019110-44-1
      Sorbic acid is a natural product that inhibits various bacteria, including sporeformers,
      • $30
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    • Isoastilbin
      TN177254081-48-0
      Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg/mL, Isoastilbin has anti-acne and tyrosinase inhibition properties. Isoastilbin shows neuroprotective, antioxidation, antimicrobial and anti-apoptotic properties and has the potential for Alzheimer s disease research
      • $129
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    • Brevilin A
      T467216503-32-5
      Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells with anti-tumor activity. Brevilin A is a selective inhibitor of JAK-STAT signal pathway by attenuating the JAKs activity and blocking STAT3 signaling (IC50 = 10.6 μM) in Cancer Cells.Brevilin A induces apoptosis and autophagy via mitochondrial pathway and PI3K/AKT/mTOR inactivation in colon adenocarcinoma cell CT26.antitumour
      • $97
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    • 8-Geranyloxypsoralen
      TN13437437-55-0
      8-Geranyloxypsoralen inhibits α2-secretase (BACE1) activity in non-competitive manner, with the IC(50) values <25.0 μM, it can induce vasorelaxation on rat arterial tissues. 8-Geranyloxypsoralen possesses nematicidal activities, the median lethal concentrations (LC(50)) is 188.3 mg/ L against B. xylophilus and is 117.5 mg/L against P. redivivus.
      • $156
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    • Cefotaxime
      T773363527-52-6
      Cefotaxime is an inhibitor of penicillin binding protein.
      • $41
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    • 5,7-DIMETHOXYFLAVONE
      T577821392-57-4
      5,7-DIMETHOXYFLAVONE possessed remarkable leishmanicidal potential.
      • $34
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