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Acetamiprid

Name: Acetamiprid
Brand: TargetMol
SKU: T14094
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T14094Cas No. 135410-20-7

Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist. Acetamiprid is a neonicotinoid insecticide used worldwide. It is shown to be associated with neuromuscular and reproductive disorders.

Acetamiprid

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Purity: 99.89%

Catalog No. T14094Cas No. 135410-20-7

Pack Size	Price	USA Warehouse	Global Warehouse
50 mg	$41	-	In Stock
100 mg	$59	-	In Stock
500 mg	$143	-	In Stock
1 mL x 10 mM (in DMSO)	$66	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.89%

Appearance:Solid

Color:White to Yellow

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

In vivo

Acetamiprid decreases body weight and mildly affects spermatogenesis [1]. It disrupts testosterone biosynthesis by reducing the conversion rate of cholesterol to testosterone and preventing cholesterol from entering Leydig cell mitochondria, causing reproductive damage in rats [2]. Additionally, it decreases the expression of testosterone-metabolism genes, nAChR subunit genes, and proliferation-associated genes in mice [1].

Chemical Properties

Molecular Weight	222.67
Formula	C₁₀H₁₁ClN₄
Cas No.	135410-20-7
Smiles	CN(Cc1ccc(Cl)nc1)C(\C)=N\C#N
Relative Density.	1.17

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 122.5 mg/mL (550.14 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (14.82 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.4910 mL	22.4548 mL	44.9095 mL	224.5475 mL
5 mM	0.8982 mL	4.4910 mL	8.9819 mL	44.9095 mL
10 mM	0.4491 mL	2.2455 mL	4.4910 mL	22.4548 mL
20 mM	0.2245 mL	1.1227 mL	2.2455 mL	11.2274 mL
50 mM	0.0898 mL	0.4491 mL	0.8982 mL	4.4910 mL
100 mM	0.0449 mL	0.2245 mL	0.4491 mL	2.2455 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc