Shopping Cart

Remove All

Your shopping cart is currently empty

Proceed to checkout Continue shopping

PDE7-IN-2

Name: PDE7-IN-2
Brand: TargetMol
SKU: T22491
Rating: 4.5 (1 reviews)

😃Good

Catalog No. T22491Cas No. 107522-19-0

PDE7-IN-2 is an inhibitor of phosphodiesterase 7 (IC50 = 2.1 µM) and can be used in Parkinson's disease studies.

PDE7-IN-2

😃Good

Catalog No. T22491Cas No. 107522-19-0

PDE7-IN-2 is an inhibitor of phosphodiesterase 7 (IC50 = 2.1 µM) and can be used in Parkinson's disease studies.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$133	35 days	35 days
5 mg	$568	35 days	35 days
10 mg	$983	35 days	35 days
25 mg	$2,230	35 days	35 days

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Appearance:Solid

Color:Yellow

Resource Download

COA

Product Introduction

Bioactivity

Description	PDE7-IN-2 is an inhibitor of phosphodiesterase 7 (IC50 = 2.1 µM) and can be used in Parkinson's disease studies.
Targets&IC50	PDE7A:2.1 μM

Chemical Properties

Molecular Weight	322.77
Formula	C₁₄H₁₁ClN₂O₃S
Cas No.	107522-19-0
Smiles	S(C1=C(N(=O)=O)C=CC(Cl)=C1)C2=C(NC(C)=O)C=CC=C2
Relative Density.	1.44 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: ≤5 mg/mL, Sonication is recommended.

DMSO: 27 mg/mL (83.65 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0982 mL	15.4909 mL	30.9818 mL	154.9091 mL
5 mM	0.6196 mL	3.0982 mL	6.1964 mL	30.9818 mL
10 mM	0.3098 mL	1.5491 mL	3.0982 mL	15.4909 mL
20 mM	0.1549 mL	0.7745 mL	1.5491 mL	7.7455 mL
50 mM	0.0620 mL	0.3098 mL	0.6196 mL	3.0982 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc