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Anti-Phospho-IRE1 (Ser724) Polyclonal Antibody
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Catalog No. TMAB-01432
Alias p-IRE1 (Ser724), p-IRE1 (S724), IRE1P, IRE1a, IRE1 (p-Ser724), IRE1 (p-S724), IRE1, hIRE1p, endoplasmic reticulum to nucleus signaling 1
Anti-Phospho-IRE1 (Ser724) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IRE1 (Ser724). Anti-Phospho-IRE1 (Ser724) Polyclonal Antibody can be used in WB.
Anti-Phospho-IRE1 (Ser724) Polyclonal Antibody
Anti-Phospho-IRE1 (Ser724) Polyclonal Antibody
😃Good
Catalog No. TMAB-01432Alias p-IRE1 (Ser724), p-IRE1 (S724), IRE1P, IRE1a, IRE1 (p-Ser724), IRE1 (p-S724), IRE1, hIRE1p, endoplasmic reticulum to nucleus signaling 1
Anti-Phospho-IRE1 (Ser724) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IRE1 (Ser724). Anti-Phospho-IRE1 (Ser724) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $222 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $529 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-IRE1 (Ser724) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IRE1 (Ser724). Anti-Phospho-IRE1 (Ser724) Polyclonal Antibody can be used in WB. |
| Synonyms | p-IRE1 (Ser724), p-IRE1 (S724), IRE1P, IRE1a, IRE1 (p-Ser724), IRE1 (p-S724), IRE1, hIRE1p, endoplasmic reticulum to nucleus signaling 1 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Pig,Cow,Horse,Sheep) |
| Verified Activity | Sample: Lane 1: Human 293T cell lysates Lane 2: Human DU145 cell lysates Lane 3: Human HeLa cell lysates Lane 4: Human Jurkat cell lysates Primary: Anti-phospho-IRE1 (Ser724) (TMAB-01432) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 107 kDa Observed band size: 130 kDa  |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Endoplasmic reticulum membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Ubiquitously expressed. High levels observed in pancreatic tissue. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | ERN2, endoplasmic reticulum to nucleus signaling 2, induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. It is pro-apoptotic and appears to play no role in the unfolded-protein response, unlike closely related proteins. |
| Immunogen | KLH conjugated synthesised phosphopeptide: human IRE1 around the phosphorylation site of Ser724 |
| Antigen Species | Human |
| Gene Name | ERN1 |
| Gene ID | |
| Protein Name | Serine/threonine-protein kinase/endoribonuclease IRE1 |
| Uniprot ID | |
| Biology Area | Other Kinases |
| Function | Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins. |
| Molecular Weight | Theoretical: 107 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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