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Iriflophenone

Name: Iriflophenone
Brand: TargetMol
SKU: TN1768
Price: 74 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1768Cas No. 52591-10-3

Iriflophenone stimulates cells proliferation in MCF-7 and T-47D human breast cancer.

Iriflophenone

😃Good

Purity: 97.90%

Catalog No. TN1768Cas No. 52591-10-3

Iriflophenone stimulates cells proliferation in MCF-7 and T-47D human breast cancer.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$74	In Stock	In Stock
5 mg	$178	In Stock	In Stock
10 mg	$287	In Stock	In Stock
25 mg	$460	In Stock	In Stock
50 mg	$592	In Stock	In Stock
100 mg	$833	In Stock	In Stock
200 mg	$1,120	-	In Stock
1 mL x 10 mM (in DMSO)	$200	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:97.90%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC LCMS

Product Introduction

Bioactivity

Description

Iriflophenone stimulates cells proliferation in MCF-7 and T-47D human breast cancer.

In vitro

2,2'-Diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity was used to evaluate the antioxidant capacity of the CPE. Experimental results concluded that ethanol concentration and solid-to-solvent ratio had significant effects (p<0.05) on the yields of polyphenol and antioxidant capacity. Extraction time had an insignificant influence on the recovery of EGCG, ECG and Iriflophenone 3-C-β-glucoside, as well as radical scavenging capacity from the CPE. The extraction parameters that exhibited maximum yields were 40% (v/v) ethanol, 1:60 (w/v) for 30 min where the TPC, TFC, TF, DPPH, EGCG, ECG and Iriflophenone 3-C-β-glucoside levels achieved were 183.5 mg GAE/g DW, 249.0 mg QE/g DW, 4.9 mg CE/g DW, 93.7%, 29.1 mg EGCG/g DW, 44.3 mg ECG/g DW and 39.9 mg Iriflophenone 3-C-β-glucoside/g DW respectively. The IC50 of the CPE was 24.6 mg/L.

Chemical Properties

Molecular Weight	246.22
Formula	C₁₃H₁₀O₅
Cas No.	52591-10-3
Smiles	Oc1ccc(cc1)C(=O)c1c(O)cc(O)cc1O
Relative Density.	1.526 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (243.68 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.0614 mL	20.3070 mL	40.6141 mL	203.0704 mL
5 mM	0.8123 mL	4.0614 mL	8.1228 mL	40.6141 mL
10 mM	0.4061 mL	2.0307 mL	4.0614 mL	20.3070 mL
20 mM	0.2031 mL	1.0154 mL	2.0307 mL	10.1535 mL
50 mM	0.0812 mL	0.4061 mL	0.8123 mL	4.0614 mL
100 mM	0.0406 mL	0.2031 mL	0.4061 mL	2.0307 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc