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Synonyms: SH3_PI3K_p85alpha, PtdIns-3-kinase regulatory subunit p85-alpha, PtdIns-3-kinase regulatory subunit alpha, PI3-kinase subunit p85-alpha, PI3-kinase regulatory subunit alpha, PI3-kinase p85 subunit gamma, PI3-kinase p85 subunit alpha, PI3K regulatory subunit alpha, PI 3-kinase p85-α, PI 3-kinase p85α, PI 3-kinase p85 α, PI 3 Kinase p85 alpha, phosphoinositide-3-kinase regulatory subunit 1, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, p85-ALPHA, P85A, p85, IMD36, GRB1, AGM7
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
| Description | Anti-PIK3R1 Antibody (9O121) is a Rabbit antibody targeting PIK3R1. Anti-PIK3R1 Antibody (9O121) can be used in FCM,ICC/IF,IHC,WB. |
| Synonyms | SH3_PI3K_p85alpha, PtdIns-3-kinase regulatory subunit p85-alpha, PtdIns-3-kinase regulatory subunit alpha, PI3-kinase subunit p85-alpha, PI3-kinase regulatory subunit alpha, PI3-kinase p85 subunit gamma, PI3-kinase p85 subunit alpha, PI3K regulatory subunit alpha, PI 3-kinase p85-α, PI 3-kinase p85α, PI 3-kinase p85 α, PI 3 Kinase p85 alpha, phosphoinositide-3-kinase regulatory subunit 1, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, p85-ALPHA, P85A, p85, IMD36, GRB1, AGM7 |
| Ig Type | IgG |
| Clone | 9O121 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Phosphatidylinositol 3-kinase (PI 3-kinase) phosphorylates the 3' OH position of the inositol ring of inositol lipids and is composed of p85 and p110 subunits. PI 3-kinase p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85α and p85β), each possessing one SH3 and two SH2 domains. PI 3-kinase p85α, also known as GRB1, phosphatidylinositol 3-kinase regulatory 1 or p85, is a 724 amino acid protein that exists as four alternatively spliced isoforms. Involved in insulin metabolism, defects in the PI 3-kinase p85α gene have been linked to insulin resistance. PI 3-kinase p85α is polyubiquitinated in T-cells by Cbl-b, and has multiple phosphorylated amino acid residues, including a phosphorylated tyrosine residue at position 467. |
| Conjucates | Unconjugated |
| Immunogen | A synthesized peptide: C-terminal human PI 3 Kinase p85 alpha |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 84 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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