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Anti-Phospho-NBN (Ser343) Polyclonal Antibody

(Synonyms: p-NBN (Ser343), p-NBN (S343), Phospho-NBN (S343), p95 protein of the MRE11/RAD50 complex, p95, Nijmegen breakage syndrome protein 1, Nijmegen breakage syndrome 1, Nijmegen breakage syndrome, nibrin, NBS1, NBS 1, NBS, NBN (p-Ser343), NBN (p-S343), MGC87362, FLJ10155, Cell cycle regulatory protein p95, ATV, AT V2, AT V1) Copy Product Info
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Synonyms: p-NBN (Ser343), p-NBN (S343), Phospho-NBN (S343), p95 protein of the MRE11/RAD50 complex, p95, Nijmegen breakage syndrome protein 1, Nijmegen breakage syndrome 1, Nijmegen breakage syndrome, nibrin, NBS1, NBS 1, NBS, NBN (p-Ser343), NBN (p-S343), MGC87362, FLJ10155, Cell cycle regulatory protein p95, ATV, AT V2, AT V1

Catalog No. TMAC-03045 Copy Product Info
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Anti-Phospho-NBN (Ser343) Polyclonal Antibody is a Rabbit antibody targeting Phospho-NBN (Ser343). Anti-Phospho-NBN (Ser343) Polyclonal Antibody can be used in WB.

Anti-Phospho-NBN
(Ser343) Polyclonal Antibody

Pack SizePriceUSA StockGlobal StockQuantity
50 µL$2177-10 days7-10 days
100 µL$3177-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-NBN (Ser343) Polyclonal Antibody is a Rabbit antibody targeting Phospho-NBN (Ser343). Anti-Phospho-NBN (Ser343) Polyclonal Antibody can be used in WB.
Synonymsp-NBN (Ser343), p-NBN (S343), Phospho-NBN (S343), p95 protein of the MRE11/RAD50 complex, p95, Nijmegen breakage syndrome protein 1, Nijmegen breakage syndrome 1, Nijmegen breakage syndrome, nibrin, NBS1, NBS 1, NBS, NBN (p-Ser343), NBN (p-S343), MGC87362, FLJ10155, Cell cycle regulatory protein p95, ATV, AT V2, AT V1
Ig Type
IgG
Reactivity
Human
Verified Activity
1. Western blot analysis of extracts from Hela cells untreated or treated with Hydroxyurea using p95/NBS1 (Phospho-Ser343) Antibody TMAC-03045.
Anti-Phospho-NBN (Ser343) Polyclonal Antibody
Application
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundMutations in p95/NBS1 gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of serine 343 (S-L-S(p)-Q-G) derived from Human p95/NBS1
Antigen Species
Human
Uniprot ID
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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