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Anti-GLUL Polyclonal Antibody

(Synonyms: GS, Glutamine Synthetase, Glutamate-Ammonia Ligase, Glutamate Decarboxylase, GLUL, GLNS) Copy Product Info
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Synonyms: GS, Glutamine Synthetase, Glutamate-Ammonia Ligase, Glutamate Decarboxylase, GLUL, GLNS

Catalog No. TMAB-00780 Copy Product Info
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Anti-GLUL Polyclonal Antibody is a Rabbit antibody targeting GLUL. Anti-GLUL Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB.
Anti-GLUL Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-GLUL Polyclonal Antibody is a Rabbit antibody targeting GLUL. Anti-GLUL Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB.
SynonymsGS, Glutamine Synthetase, Glutamate-Ammonia Ligase, Glutamate Decarboxylase, GLUL, GLNS
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human,Pig,Cow,Sheep)
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Mitochondrion.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundGlutamine Synthetase catalyzes the conversion of ammonia and glutamate to glutamine. It is found in astrocytes as an octamer of identical 42 kDa subunits. The function of Glutamine Synthetase is the detoxification of brain ammonia. It also has an important role in the metabolic regulation of neurotransmitter glutamate. Because of the multiple functions and importance of Glutamine Synthetase in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of Glutamine Synthetase is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer's disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation. The level of expression of Glutamine Synthetase is increased during ischemia in vivo or hypoxia in culture.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Glutamine synthetase
Antigen Species
Human
Gene Name
GLUL
Gene ID
Protein Name
Glutamine synthetase
Uniprot ID
Biology Area
Alzheimer's disease,Glutamate
Function
This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). Essential for proliferation of fetal skin fibroblasts.
Chemical Properties
Molecular WeightTheoretical: 42 kDa. Actual: 42 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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