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Hypaconine

Name: Hypaconine
Brand: TargetMol
SKU: TN1754
Price: 93 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. TN1754Cas No. 63238-68-6

Hypaconine, a C19-diterpenoid alkaloid isolated from Aconitum and Delphinium spp., exhibits strong cardiac activity.

Hypaconine

🥰Excellent

Catalog No. TN1754Cas No. 63238-68-6

Hypaconine, a C19-diterpenoid alkaloid isolated from Aconitum and Delphinium spp., exhibits strong cardiac activity.

Pack Size	Price	Availability
1 mg	$93	In Stock
5 mg	$239	In Stock
10 mg	$378	In Stock
25 mg	$635	In Stock
50 mg	$885	In Stock
100 mg	$1,230	In Stock
200 mg	$1,670	In Stock
1 mL x 10 mM (in DMSO)	$278	In Stock

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Purity:≥98%

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COA HNMR

Product Introduction

Bioactivity

Description	Hypaconine, a C19-diterpenoid alkaloid isolated from Aconitum and Delphinium spp., exhibits strong cardiac activity.
In vitro	Among them, eleven compounds exhibited cardiac activity, with average rate of amplitude increase in the range of 16-118%. Compound 7, mesaconine (17), Hypaconine (25), and beiwutinine (26) exhibited strong cardiac activities relative to the reference drug.

Chemical Properties

Molecular Weight	469.57
Formula	C₂₄H₃₉NO₈
Cas No.	63238-68-6
Smiles	[H][C@@]12C[C@@]3(O)[C@H](O)[C@]1([H])[C@@](O)(C1[C@H](OC)[C@@]4([H])C22C1N(C)C[C@]4(COC)CC[C@@H]2OC)[C@@H](O)[C@@H]3OC
Relative Density.	1.39 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (117.13 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.26 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1296 mL	10.6480 mL	21.2961 mL	106.4804 mL
5 mM	0.4259 mL	2.1296 mL	4.2592 mL	21.2961 mL
10 mM	0.2130 mL	1.0648 mL	2.1296 mL	10.6480 mL
20 mM	0.1065 mL	0.5324 mL	1.0648 mL	5.3240 mL
50 mM	0.0426 mL	0.2130 mL	0.4259 mL	2.1296 mL
100 mM	0.0213 mL	0.1065 mL	0.2130 mL	1.0648 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc