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IGFBP-7 Protein, Human, Recombinant (aa 30-282, His)
(Synonyms: TAF, RAMSVPS, PSF, MAC25, insulin-like growth factor binding protein 7, IGFBPRP1, IGFBP-7v, IGFBP-7, IBP-7, FSTL2, AGM) Copy Product InfoSynonyms: TAF, RAMSVPS, PSF, MAC25, insulin-like growth factor binding protein 7, IGFBPRP1, IGFBP-7v, IGFBP-7, IBP-7, FSTL2, AGM
Catalog No. TMPY-02533 Copy Product Info
Purity: 95.7%
IGFBP-7 Protein, Human, Recombinant (aa 30-282, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.6 kDa and the accession number is Q16270.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $63 | - | In Stock | |
| 10 µg | $100 | - | In Stock | |
| 20 µg | $163 | - | In Stock | |
| 50 µg | $320 | - | In Stock | |
| 100 µg | $518 | 7-10 days | 7-10 days | |
| 200 µg | $837 | 7-10 days | 7-10 days | |
| 500 µg | $1,580 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95.7%
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Human IGFBP7 His at 2 μg/ml (100 μl/well) can bind Human CD93 (hFc Tag). The EC50 is 60-400 ng/ml. |
| Description | IGFBP-7 Protein, Human, Recombinant (aa 30-282, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.6 kDa and the accession number is Q16270. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | N-His |
| Accession Number | Q16270 |
| Construction | A DNA sequence encoding the human IGFBP7 (Q16270) (Asp 30-Leu 282) was fused with a polyhistidine tag at the N-terminus. Predicted N terminal: His |
| Protein Purity | > 92 % as determined by SDS-PAGE  |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot. |
| Synonyms | TAF, RAMSVPS, PSF, MAC25, insulin-like growth factor binding protein 7, IGFBPRP1, IGFBP-7v, IGFBP-7, IBP-7, FSTL2, AGM |
| Research Background | Insulin-like growth factor-binding protein 7 (IGFBP7) is a member of the IGFBP family. It has been identified in colorectal adenocarcinoma (CRC) cell lines. The Insulin-like growth factor-binding protein also known as IGFBP serves as a carrier protein for Insulin-like growth factor 1. IGFBPs are distinct but are sharing regions with strong homology. All members of the IGFBP family bind IGF-I and IGF-II with about equal affinity. Insulin-like growth factor (IGF) binding proteins (IGFBPs) have been shown to either inhibit or enhance the action of IGF or act in an IGF-independent manner in the prostate. IGFBP7 could inhibit cell growth, decrease soft agar colony formation activity, and induce apoptosis in RKO and SW620 cells. There is mounting evidence that the structure of the IGFBP proteins plays a key role in the regulation of IGF bioavailability, by modulating its molecular size, capillary membrane permeability, target tissue specificity, cell membrane adherence, and IGF affinity. |
| Molecular Weight | 28.6 kDa (predicted); 36 kDa (reducing conditions) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: IGFBP-7 Protein, Human, Recombinant (aa 30-282, His) chemical structure | IGFBP-7 Protein, Human, Recombinant (aa 30-282, His) molecular weight
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