Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JPS016, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC). It serves as a potent HDAC1/2 degrader, resulting in a significant increase in differentially expressed genes and enhanced apoptosis in HCT116 cells [1].
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Description | JPS016, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC). It serves as a potent HDAC1/2 degrader, resulting in a significant increase in differentially expressed genes and enhanced apoptosis in HCT116 cells [1]. |
Molecular Weight | 898.12 |
Formula | C48H63N7O8S |
CAS No. | 2669785-77-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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JPS016 2669785-77-5 inhibitor inhibit