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CPDA

Name: CPDA
Brand: TargetMol
SKU: T10877
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T10877Cas No. 1415834-63-7

CPDA is a new potent inhibitor of SH2 domain-containing inositol phosphatase 2 (SHIP2).

CPDA

🥰Excellent

Purity: 98.34%

Catalog No. T10877Cas No. 1415834-63-7

CPDA is a new potent inhibitor of SH2 domain-containing inositol phosphatase 2 (SHIP2).

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$41	In Stock	In Stock
10 mg	$68	In Stock	In Stock
25 mg	$135	In Stock	In Stock
50 mg	$227	In Stock	In Stock
100 mg	$358	In Stock	In Stock
200 mg	$492	-	In Stock
1 mL x 10 mM (in DMSO)	$45	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:98.34%

Resource Download

COA LCMS HNMR HPLC

Product Introduction

Bioactivity

Description	CPDA is a new potent inhibitor of SH2 domain-containing inositol phosphatase 2 (SHIP2).
In vitro	CPDA enhances insulin signaling. CPDA was found to enhance in vitro insulin signaling through the Akt pathway more efficiently than the previously reported SHIP2 inhibitor AS1949490, and ameliorated abnormal glucose metabolism in diabetic (db/db) mice.
In vivo	CPDA significantly enhances abnormal glucose metabolism in diabetic animals, as evidenced by its effectiveness in improving glucose metabolism in db/db mice.

Chemical Properties

Molecular Weight	388.8
Formula	C₂₀H₁₅ClF₂N₂O₂
Cas No.	1415834-63-7
Smiles	Fc1cccc(F)c1CC(=O)Nc1cc(OCc2ccc(Cl)cc2)ccn1
Relative Density.	1.381 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (128.6 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.14 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5720 mL	12.8601 mL	25.7202 mL	128.6008 mL
5 mM	0.5144 mL	2.5720 mL	5.1440 mL	25.7202 mL
10 mM	0.2572 mL	1.2860 mL	2.5720 mL	12.8601 mL
20 mM	0.1286 mL	0.6430 mL	1.2860 mL	6.4300 mL
50 mM	0.0514 mL	0.2572 mL	0.5144 mL	2.5720 mL
100 mM	0.0257 mL	0.1286 mL	0.2572 mL	1.2860 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc