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B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled

(Synonyms: PSEC0249, PRO352, CD276, B7-H3, B7H3, B7 homolog 3,  UNQ309) Copy Product Info

Synonyms: PSEC0249, PRO352, CD276, B7-H3, B7H3, B7 homolog 3,  UNQ309

Catalog No. TMPK-01016 Copy Product Info
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 50.1 kDa and the accession number is Q5ZPR3-2.
Pack SizePriceUSA StockGlobal StockQuantity
10 µg$2487-10 days7-10 days
20 µg$4157-10 days7-10 days
50 µg$8287-10 days7-10 days
100 µg$1,4007-10 days7-10 days
200 µg$2,1307-10 days7-10 days
500 µg$3,7207-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 50.1 kDa and the accession number is Q5ZPR3-2.
Species
Human
Expression System
HEK293 Cells
TagC-hFc
Accession NumberQ5ZPR3-2
ConstructionLeu29-Pro245
Protein Purity
> 95% as determined by Tris-Bis PAGE
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as 0.22 μm filtered solution in PBS (pH 7.4).
SynonymsPSEC0249, PRO352, CD276, B7-H3, B7H3, B7 homolog 3,  UNQ309
Research Background
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction.
Chemical Properties
Molecular Weight50.1 kDa (predicted). Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
ShippingProteins are shipped with blue ice.
StorageIt is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled chemical structure | B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled molecular weight