B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled

B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction.

Pack Size	Availability	Price/USD
100 μg	5 days	$ 1,400.00
500 μg	5 days	$ 3,720.00
1 mg	5 days	$ 6,210.00

Pack Size

Availability

Price/USD

Quantity

100 μg

5 days

$ 1,400.00

500 μg

5 days

$ 3,720.00

1 mg

5 days

$ 6,210.00

Description

Species	Human
Expression System	HEK293
Tag	C-hFc
Accession Number	Q5ZPR3-2
Synonyms	B7H3, UNQ309, PRO352, PSEC0249, B7 homolog 3, B7-H3, CD276
Construction	Recombinant FITC-Labeled Human B7-H3/CD276 Protein is expressed from HEK293 with hFc tag at the C-Terminus. It contains Leu29-Pro245.[Accession \|Q5ZPR3-2]
Protein Purity	> 95% as determined by Tris-Bis PAGE
Molecular Weight	The protein has a predicted MW of 50.1 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result.

Endotoxin	Less than 1EU per μg by the LAL method.
Formulation	Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Stability & Storage	Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Research Background	B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction.