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B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled

TargetMol | SPR
Catalog No. TMPK-01016 Copy Product Info
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 50.1 kDa and the accession number is Q5ZPR3-2.

B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled

Catalog No. TMPK-01016
Copy Product Info
TargetMol | SPR

B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 50.1 kDa and the accession number is Q5ZPR3-2.

B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$1487-10 days7-10 days
10 μg$2487-10 days7-10 days
20 μg$4157-10 days7-10 days
50 μg$8287-10 days7-10 days
100 μg$1,4007-10 days7-10 days
200 μg$2,1307-10 days7-10 days
500 μg$3,7207-10 days7-10 days
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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)
For research use only—not for human use. No sales to individuals. Use as intended only.
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Biological Activity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 50.1 kDa and the accession number is Q5ZPR3-2.
Species
Human
Expression System
HEK293 Cells
TagC-hFc
Accession NumberQ5ZPR3-2
Synonyms
PSEC0249,PRO352,CD276,B7-H3,B7H3,B7 homolog 3, UNQ309
Construction
Leu29-Pro245
Protein Purity
> 95% as determined by Tris-Bis PAGE
Molecular Weight50.1 kDa (predicted). Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as 0.22 μm filtered solution in PBS (pH 7.4).
Stability & Storage
It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingProteins are shipped with blue ice.
Research Background
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction.

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